Mouse Anti-SYCP3 Recombinant Antibody (VS3-CJ40) (CAT#: VS3-CJ40)

• Immunogen
• Recombinant full length of human SYCP3

• Host Species
• Mouse

• Type
• Mouse IgG1

• Specificity
• Human SYCP3

• Species Reactivity
• Human

• Applications
• ELISA

• Conjugate
• Unconjugated

• Purification
• Protein G affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Concentration
• 1 mg/mL (lot specific)

• Buffer
• 50% Glycerol, 1% BSA, PBS, pH7.4.

• Preservative
• 0.02% sodium azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• This antibody has been tested for use in ELISA (1:5000-1:20000).

• Alternative Names
• COR1; RPRGL4; SCP3; SPGF4

• Gene ID
• 50511

• UniProt ID
• Q8IZU3

• Sequence Similarities
• Belongs to the XLR/SYCP3 family.

• Cellular Localization
• Centromere, Chromosome, Nucleus

• Post Translation Modifications
• Phosphorylated.

• Protein Refseq
• NP_001171419.1; NP_001171420.1; NP_710161.1

• Function
• Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity).
  Required for normal meiosis during spermatogenesis and male fertility (PubMed:14643120).
  Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).

Isotype Control

• MOB-065CQ
• Mouse IgG1 Isotype Control Antibody

Secondary Antibody

• 2RD-A1460-YJ
• Goat Anti-Mouse IgG1 Secondary antibody

• 2RD-A1562-YJ
• Rabbit Anti-Mouse IgG1 Secondary antibody (Clone RM106)

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS