DrugMonitor™ Anti-Thioredoxin Antibody (VS-1124-YC845) (CAT#: VS-1124-YC845)

Thioredoxin, a small dithiol protein, serves as a specific reductant for major allergenic proteins found in both animal and plant food products. This 12-kilodalton (kDa) oxidoreductase enzyme, encoded by the TXN and TXN2 genes, contains a dithiol-disulfide active site and plays a crucial antioxidant role in neutralizing food allergens and participating in redox signaling. Allergenic proteins with disulfide bonds become inactive when reduced by thioredoxin. The DrugMonitor™ Anti-Thioredoxin Antibody, an ADA against Thioredoxin, is developed in rabbits immunized with Thioredoxin. Suitable for ELISA, PK, and PD analyses, it serves as a reference standard in ADA assays and is an effective tool for drug monitoring, allowing for the determination of Thioredoxin levels and the assessment of its efficacy.

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Specifications

  • Host Animal
  • Rabbit
  • Specificity
  • Thioredoxin
  • Target
  • Thioredoxin
  • Immunogen
  • Thioredoxin-BSA
  • Type
  • Rabbit IgG
  • Species Reactivity
  • Non-species dependent
  • Purity
  • >95%
  • Purification
  • Protein G
  • Applications
  • ELISA, PK/PD, ADA control
  • Format
  • Liquid
  • Concentration
  • Batch-dependent
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
  • Generic name
  • Thioredoxin

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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