Human Anti-TICAGRELOR Recombinant Antibody (clone Fab72) (CAT#: HPAB-2078-FY)

This product is a recombinant human antibody that recognizes TICAGRELOR. The monoclonal human antibody Fab72 reacts with the epitope of TICAGRELOR.

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Inhib

Figure 1 Iillustrates correlation of scFv binding to biotinylated linker ticagrelor (x- axis) and binding to biotinylated linker ticagrelor in a 50-fold excess of unmodified ticagrelor (y- axis).

Figure 1 Iillustrates correlation of scFv binding to biotinylated linker ticagrelor (x- axis) and binding to biotinylated linker ticagrelor in a 50-fold excess of unmodified ticagrelor (y- axis).

The inhibition of scFv binding in the presence of excess unmodified ticagrelor is shown with lines for 0%, 50%, 80% and 90% inhibition.

ELISA

Figure 2 Provides competition curves for parent TICA0072 and optimized variants TICA0152, TICA0162 and TICA0212 Fabs in the second generation epitope competition assay.

Figure 2 Provides competition curves for parent TICA0072 and optimized variants TICA0152, TICA0162 and TICA0212 Fabs in the second generation epitope competition assay.

Inhib

Figure 3 Shows the results of TICA0072 concentration dependent reversal of ticagrelor.

Figure 3 Shows the results of TICA0072 concentration dependent reversal of ticagrelor.

TICA0072 reversal of ticagrelor and TAM inhibition of P2Yi2 signalling.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • TICAGRELOR
  • Clone
  • Fab72
  • Applications
  • Inhib, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The TICAGRELOR antibody has been reported in applications of Inhibition, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • TICAGRELOR

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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