Rabbit Anti-TMEM30B Recombinant Antibody (clone R09-9G7)

CAT#: VS3-FY1905

This anti-Transmembrane protein 30B antibody detected positive in western blot analysis of TMEM30B in MCF-7 lysates. The recombinant monoclonal antibody effectively recognizes human TMEM30B. This R09-9G7 antibody is validated for western blot analysis of TMEM30B in MCF-7 lysates.

Tested Data
Figure 1 Anti-TMEM30B Antibody (VS3-FY1905) in WB.

Specifications

  • Immunogen
  • Recombinant human TMEM30B protein
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human TMEM30B
  • Species Reactivity
  • Human
  • Clone
  • R09-9G7
  • Applications
  • Western Blot
  • MW
  • The calculated weight of the target protein is approximately 39 kDa, while the observed molecular weight stands at 39 kDa.
  • Related Disease
  • Foster-Kennedy Syndrome and Cerebellopontine Angle Meningioma

Product Property

  • Purification
  • Affinity Purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/1000

Target

  • Alternative Names
  • Transmembrane Protein 30B; P4-ATPase Flippase Complex Beta Subunit TMEM30B; CDC50B; Cell Cycle Control Protein 50B
  • Sequence Similarities
  • Belongs to the CDC50/LEM3 family.
  • Cellular Localization
  • Cell membrane, Membrane
  • Post Translation Modifications
  • Glycosylation at Asn75, Asn213, and Asn286 (NX_Q3MIR4 [NX_Q3MIR4-1])
    Modification sites at PhosphoSitePlus (Q3MIR4)
    Glycosylation from GlyGen (Q3MIR4) 3 sites
  • Function
  • Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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