Specifications

Immunogen
Synthetic peptide of human TRPV5

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human, Mouse and Rat TRPV5

Species Reactivity
Human, Mouse, Rat

Clone
R03-7A4

Applications
Western Blot, Immunoprecipitation

MW
The calculated weight of the target protein is approximately 83 kDa, while the observed molecular weight stands at 83 kDa.

Related Disease
Urolithiasis and Pseudohypoaldosteronism

Product Property

Purification
Affinity Purified

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Transient Receptor Potential Cation Channel Subfamily V Member 5; Epithelial Calcium Channel 1; Calcium Transport Protein 2; Osm-9-Like TRP Channel 3; OTRPC3; ECAC1

Gene ID
56302

UniProt ID
Q9NQA5

Sequence Similarities
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV5 sub-subfamily.

Cellular Localization
Cell membrane, Membrane

Post Translation Modifications
Glycosylated. (Q9NQA5-TRPV5_HUMAN)
Glycosylation at Asn358 (NX_Q9NQA5 [NX_Q9NQA5-1])
Modification sites at PhosphoSitePlus (Q9NQA5)
Glycosylation from GlyGen (Q9NQA5) 1 site

Protein Refseq
NP_062815.3

Function
Constitutively active calcium selective cation channel thought to be involved in Ca²⁺ reabsorption in kidney and intestine.
Required for normal Ca²⁺ reabsorption in the kidney distal convoluted tubules (By similarity).
The channel is activated by low internal calcium level and the current exhibits an inward rectification.

Recommended Products

Secondary Antibody

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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IgG Antibody Products Rabbit Monoclonal Antibody Products

CAT	Product Name	Application	Type
MOB-2037CT	Recombinant Mouse anti-Human TRPV5 Monoclonal antibody (EML1796)	ICC/IF, WB

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