Mouse Anti-UBL5 Recombinant Antibody (VS3-FY2911)

CAT#: VS3-FY2911

This anti-UBL5 product is a recombinant mouse monoclonal antibody that binds to human UBL5 protein. It cross-reacts with mouse species. The calculated molecular weight of the protein is about 8.5 kDa. The antibody can be utilized for detection of target protein by Western Blot (1/500-1/2000).

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (NB-4)

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human and Mouse UBL5
  • Species Reactivity
  • Human, Mouse
  • Applications
  • Western Blot
  • Conjugate
  • Unconjugated, FITC
  • MW
  • The molecular weight of the target protein is approximately 8.5 kDa.
  • Related Disease
  • Fanconi Anemia, Complementation Group I

Product Property

  • Clonality
  • Monoclonal Antibody
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • Western Blot: 1/500-1/2000

Target

  • Alternative Names
  • Ubiquitin Like 5; Testicular Tissue Protein Li 217; Ubiquitin-Like Protein 5; Ubiquitin-Like 5; Beacon; HUB1
  • Cellular Localization
  • Cytoplasm
    Nucleus
    Nucleus, Cajal body
  • Post Translation Modifications
  • Ubiquitination at Lys41 and Lys46 (NX_Q9BZL1 [NX_Q9BZL1-1])
    Modification sites at PhosphoSitePlus (Q9BZL1)
    Glycosylation from GlyGen (Q9BZL1) 1 site, 1 O-linked glycan (1 site)
  • Function
  • Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins (PubMed:25092792).
    Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity.
    Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers (PubMed:25862789).
    Plays also a protective role against ER stress-induced apoptosis.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Secondary Antibody

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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