Mouse Anti-UBL5 Recombinant Antibody (VS3-FY2911) (CAT#: VS3-FY2911)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and Mouse UBL5

• Species Reactivity
• Human, Mouse

• Applications
• Western Blot

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 8.5 kDa.

• Related Disease
• Fanconi Anemia, Complementation Group I

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000

• Alternative Names
• Ubiquitin Like 5; Testicular Tissue Protein Li 217; Ubiquitin-Like Protein 5; Ubiquitin-Like 5; Beacon; HUB1

• Gene ID
• 59286

• UniProt ID
• Q9BZL1

• Cellular Localization
• Cytoplasm
  Nucleus
  Nucleus, Cajal body

• Post Translation Modifications
• Ubiquitination at Lys41 and Lys46 (NX_Q9BZL1 [NX_Q9BZL1-1])
  Modification sites at PhosphoSitePlus (Q9BZL1)
  Glycosylation from GlyGen (Q9BZL1) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_001041706.1; NP_077268.1

• Function
• Ubiquitin-like protein that plays a role in cell proliferation and sister chromatid cohesion by associating with spliceosomal proteins (PubMed:25092792).
  Participates thereby in pre-mRNA splicing by maintaining spliceosome integrity.
  Promotes the functional integrity of the Fanconi anemia DNA repair pathway by interacting with FANCI component and subsequently mediating the formation of FANCI homodimers (PubMed:25862789).
  Plays also a protective role against ER stress-induced apoptosis.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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