Rabbit Anti-UFD1 Recombinant Antibody (clone R09-7G5) (CAT#: VS3-FY1929)
This anti-UFD1 antibody detected positive in western blot analysis of UFD1L in Hela lysates. The recombinant monoclonal antibody demonstrates high specificity in target human UFD1. This R09-7G5 antibody is validated for western blot analysis of UFD1L in Hela lysates.
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WB
Figure 1 Anti-UFD1 Antibody (VS3-FY1929) in WB.
The UFD1L expression in Hela lysates were detected using the anti-UFD1 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human UFD1L
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human UFD1
- Species Reactivity
- Human
- Clone
- R09-7G5
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 35 kDa, while the observed molecular weight stands at 40 kDa.
- Related Disease
- Chromosome 22Q11.2 Deletion Syndrome, Distal and Digeorge Syndrome
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Ubiquitin Recognition Factor In ER Associated Degradation 1; UB Fusion Protein 1; UFD1L; Ubiquitin Recognition Factor In ER-Associated Degradation Protein 1; Ubiquitin Fusion Degradation Protein 1 Homolog; Ubiquitin Fusion Degradation 1 Like (Yeast); Ubiquitin Fusion Degradation Protein 1; Ubiquitin Fusion Degradation 1-Like; Ubiquitin Fusion Degradation 1 Like
- Gene ID
- 7353
- UniProt ID
- Q92890
- Sequence Similarities
- Belongs to the UFD1 family.
- Cellular Localization
- Cytoplasm, Nucleus
- Post Translation Modifications
- Ubiquitination at Lys45, Lys68, Lys139, Lys264, and Lys267 (NX_Q92890 [NX_Q92890-2])
Modification sites at PhosphoSitePlus (Q92890)
Glycosylation from GlyGen (Q92890) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_047297442.1; XP_047297443.1; XP_047297444.1; XP_054181874.1; XP_054181875.1
- Function
- Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures (By similarity).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK78 | Mouse Anti-UFD1 Recombinant Antibody (clone F3-A6) | WB, ELISA | Mouse IgG2b |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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