Rabbit Anti-VPS41 Recombinant Antibody (clone R08-1J7) (CAT#: VS3-FY1937)
This R08-1J7 recombinant monoclonal antibody is specifically created to target human VPS41. It cross-reacts with mouse, rat. This VPS41 antibody is guaranteed for western blot analysis of VPS41 in rat heart lysates.
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WB
Figure 1 Anti-VPS41 Antibody (VS3-FY1937) in WB.
The VPS41 expression in rat heart lysates were detected using the anti-VPS41 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human VPS41
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat VPS41
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R08-1J7
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 99 kDa, while the observed molecular weight stands at 99 kDa.
- Related Disease
- Spinocerebellar Ataxia, Autosomal Recessive 29 and Spinocerebellar Ataxia, Autosomal Recessive 4
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- VPS41, HOPS Complex Subunit; S53; Vacuolar Protein Sorting-Associated Protein 41 Homolog; Vacuolar Protein Sorting 41 Homolog (S. Cerevisiae); Vacuolar Protein Sorting 41 (Yeast Homolog); Vacuolar Protein Sorting 41 (Yeast)
- Gene ID
- 27072
- UniProt ID
- P49754
- Sequence Similarities
- Belongs to the VPS41 family.
- Cellular Localization
- Cytoplasm, Cytoplasmic vesicle, Endosome, Golgi apparatus, Lysosome, Membrane
- Post Translation Modifications
- Ubiquitination at Lys762 (NX_P49754 [NX_P49754-1])
Modification sites at PhosphoSitePlus (P49754)
Glycosylation from GlyGen (P49754) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016867477.1; XP_054213879.1; NP_055211.2; NP_542198.2
- Function
- Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3850 | Rabbit Anti-VPS41 Recombinant Antibody (clone DS3850AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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