Rabbit Anti-XRCC6 Recombinant Antibody (clone R06-3F1) (CAT#: VS3-FY2019)
This marvelous product is a rabbit recombinant antibody that with high affinity in binding to human XRCC6. It is suitable for use in a variety of assays, including WB, IHC-P, IP. This R06-3F1 antibody is validated for western blot analysis of Ku70 in Hela, Ramos lysates and immunohistochemistry analysis of paraffin-embedded human tonsil.
Specific Inquiry
WB
Figure 1 Anti-XRCC6 Antibody (VS3-FY2019) in WB.
The Ku70 expression in Hela, Ramos lysates were detected using the anti-Ku70 by western blot assay.
IHC
Figure 2 Anti-XRCC6 Antibody (VS3-FY2019) in IHC.
Immunohistochemistry staining of paraffin-embedded human tonsil using the anti-Ku70 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Specifications
- Immunogen
- Synthetic peptide of human Ku70
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human XRCC6
- Species Reactivity
- Human
- Clone
- R06-3F1
- Applications
- Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 70 kDa, while the observed molecular weight stands at 70 kDa.
- Related Disease
- Lupus Erythematosus and Nijmegen Breakage Syndrome
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Immunoprecipitation: 1/20
Target
- Alternative Names
- X-Ray Repair Cross Complementing 6; XRCC6
- Gene ID
- 2547
- UniProt ID
- P12956
- Cellular Localization
- Chromosome, Nucleus
- Post Translation Modifications
- Phosphorylation by PRKDC may enhance helicase activity.
Phosphorylation of Ser-51 does not affect DNA repair.
ADP-ribosylated by PARP3. (P12956-XRCC6_HUMAN)
Ubiquitination at Lys123, Lys129, Lys100, Lys114, Lys182, Lys238, Lys287, Lys317, Lys351, Lys357, Lys445, Lys451, Lys461, Lys565, Lys570, Lys575, and Lys605 (NX_P12956 [NX_P12956-1])
Modification sites at PhosphoSitePlus (P12956)
Glycosylation from GlyGen (P12956) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_047297260.1; XP_054181436.1; NP_001275905.1; NP_001275906.1; NP_001275907.1
- Function
- Required for double-strand break repair and V(D)J recombination.
Also has a role in chromosome translocation.
Has a role in chromosome translocation.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "XRCC6"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3897 | Rabbit Anti-XRCC6 Recombinant Antibody (clone DS3897AB) | ICC, IF, IHC-P, WB | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0907-CN | Rabbit Anti-XRCC6 Recombinant Antibody (clone JM61-31) | WB, IP, IF, IHC, FC | Rabbit IgG |
| MRO-0908-CN | Mouse Anti-XRCC6 Recombinant Antibody (clone D1-A6) | WB, IHC | Mouse IgG2a |
| MRO-2001-CN | Rabbit Anti-XRCC6 Polyclonal Antibody (MRO-2001-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-XY1608 | Mouse Anti-XRCC6 Recombinant Antibody (clone 2F7F5) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS3-XY1609 | Mouse Anti-XRCC6 Recombinant Antibody (clone 6C8G7) | ELISA, WB, FC, ICC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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