Mouse Anti-XRN1 Recombinant Antibody (VS3-FY2922) (CAT#: VS3-FY2922)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and Mouse XRN1

• Species Reactivity
• Human, Mouse

• Applications
• Western Blot

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 194.1 kDa.

• Related Disease
• Murray Valley Encephalitis and Osteogenic Sarcoma

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000

• Gene ID
• 54464

• UniProt ID
• Q8IZH2

• Sequence Similarities
• Belongs to the 5'-3' exonuclease family.

• Cellular Localization
• Cytoplasm

• Post Translation Modifications
• Ubiquitination at Lys79 and Lys847 (NX_Q8IZH2 [NX_Q8IZH2-1])
  Modification sites at PhosphoSitePlus (Q8IZH2)
  Glycosylation from GlyGen (Q8IZH2) 4 sites, 1 O-linked glycan (4 sites)

• Protein Refseq
• XP_011511221.1; XP_011511222.1; XP_016862129.1; XP_016862130.1

• Function
• Binds to RNA and DNA (By similarity).
  Plays a role in replication-dependent histone mRNA degradation.
  May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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