Rabbit Anti-YTHDC2 Recombinant Antibody (VS3-FY2924)
CAT#: VS3-FY2924
The anti-YTHDC2 antibody is a rabbit recombinant monoclonal antibody, which has been intricately crafted to target the human YTHDC2 protein. This monoclonal antibody proves valuable in disease research related to Wilms Tumor 1 and Uterine Corpus Cancer. It is recommended for detection of target protein by Immunoprecipitation (1/20), Western Blot (1/500-1/1000).
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human YTHDC2
- Species Reactivity
- Human
- Applications
- Western Blot, Immunoprecipitation
- Conjugate
- Unconjugated, FITC
- Related Disease
- Wilms Tumor 1 and Uterine Corpus Cancer
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunoprecipitation: 1/20
Western Blot: 1/500-1/1000
Target
- Alternative Names
- YTH Domain Containing 2; Probable ATP-Dependent RNA Helicase YTHDC2; CsA-Associated Helicase-Like Protein; YTH Domain-Containing Protein 2; EC 3.6.4.13; EC 3.6.1; CAHL
- Gene ID
- 64848
- UniProt ID
- Q9H6S0
- Sequence Similarities
- Belongs to the DEAD box helicase family. DEAH subfamily.
- Cellular Localization
- Cytoplasm
Cytoplasm, perinuclear region
- Post Translation Modifications
- Ubiquitination at Lys1307 (NX_Q9H6S0 [NX_Q9H6S0-1])
Modification sites at PhosphoSitePlus (Q9H6S0)
Glycosylation from GlyGen (Q9H6S0) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_011541884.1; XP_011541888.1; XP_047273483.1; XP_047273484.1
- Function
- Acts by binding and promoting degradation of m6A-containing mRNAs: the 3'-5' RNA helicase activity is required for this process and RNA degradation may be mediated by XRN1 exoribonuclease (PubMed:29033321).
Required for both spermatogenesis and oogenesis (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "YTHDC2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1235 | Rabbit Anti-Ythdc2 Recombinant Antibody (VS13-YC1235) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2508 | Anti-YTHDC2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY7984 | Anti-Human YTHDC2 Immunohistochemistry Kit | IHC |
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