Cuproptosis / Proteotoxic Stress Antibody Panel (DLAT, DLST, HSPA1A)

CAT#: VS-0725-YC6

The Cuproptosis / Proteotoxic Stress Antibody Panel are sets of 3 antibodies specifically designed for the simultaneous detection of key proteins involved in these critical pathways. The antibody panel can be used to explore emerging mechanisms of cell death and cellular stress.

Sub Cat Component Name Clone Type Target Species Reactivity Applications  
MOR-1001 Hi-Affi™ Rabbit Anti-DLST Recombinant Antibody (clone DS1001AB) DS1001AB Rabbit IgG DLST Mouse, Rat, Human WB, ICC, IF, IP, IHC-P
HPAB-0243-YC Mouse Anti-HSPA1A Recombinant Antibody (HPAB-0243-YC) Mouse IgG HSPA1A Human ELISA, FC
VS-0725-YC82 Mouse Anti-DLAT Recombinant Antibody Mouse IgG DLAT Human, Mouse ICC, IF, IP, WB
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Specifications

  • Targets
  • DLAT, DLST, HSPA1A
  • Species Reactivity
  • Human
  • Research Area
  • Cuproptosis and Proteotoxic Stress
  • Introduction
  • Cuproptosis is a recently identified form of regulated cell death (RCD) that is uniquely triggered by excessive intracellular copper accumulation. Distinct from other well-known RCD modalities like apoptosis, necroptosis, or ferroptosis, cuproptosis directly impacts mitochondrial respiration and protein homeostasis. While copper is an essential trace element vital for numerous enzymatic functions, including those in mitochondrial respiration, an imbalance leading to its overload can become highly cytotoxic.
  • Storage
  • Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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