DRB1*01:01/HBV env (QAGFFLLTRILTIPQS) MHC Monomer (CAT#: MHC-YF076)
This product is a MHC monomer of biotinylated peptide/MHC complex composed env-derived peptide of QAGFFLLTRILTIPQS sequence covering 179-194 and DRB1*01:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- DRB1*01:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- env
- Antigen Species
- HBV
- Peptide
- QAGFFLLTRILTIPQS
- Range
- 179-194
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane. In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.
- Alternative Names
- Large envelope protein; L glycoprotein; L-HBsAg; Large S protein; Large surface protein;Major surface antigen
- Gene ID
- 944569
- UniProt ID
- P03140
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-055 | Recombinant Mouse Anti-HBV PS1 peptide (HQLDPAFGANSTNPD) Antibody (PC282 ) | Neut | IgG |
| PABZ-055 | Recombinant Mouse Anti-HBV PS1 peptide (HQLDPAFGANSTNPD) Antibody (PC283) | Neut | IgG |
| PABW-055 | Recombinant Mouse Anti-HBV PS1 peptide (HQLDPAFGANSTNPD) Antibody (PC287) | Neut | IgG |
| PABC-115 | Recombinant Human Anti-SCV S RBD Antibody (80R) | Neut | IgG |
Fab Fragment Antibody
scFv Fragment Antibody
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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