DRB1*04:01/EBV EBNA1 (AEGLRALLARSHVER) MHC Monomer (CAT#: MHC-YF068)
This product is a MHC monomer of biotinylated peptide/MHC complex composed EBNA1-derived peptide of AEGLRALLARSHVER sequence covering 482-496 and DRB1*04:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- EBNA1
- Antigen Species
- EBV
- Peptide
- AEGLRALLARSHVER
- Range
- 482-496
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- Plays an essential role in replication and partitioning of viral genomic DNA during latent viral infection. During this phase, the circular double-stranded viral DNA undergoes replication once per cell cycle and is efficiently partitioned to the daughter cells. EBNA1 activates the initiation of viral DNA replication through binding to specific sites in the viral latent origin of replication, oriP. Additionally, it governs the segregation of viral episomes by mediating their attachment to host cell metaphase chromosomes. Also activates the transcription of several viral latency genes. Finally, it can counteract the stabilization of host p53/TP53 by host USP7, thereby decreasing apoptosis and increasing host cell survival.
- Alternative Names
- EBNA-1; EBV EBNA1; EBNA1
- Gene ID
- 3783709
- UniProt ID
- P03211
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF066 | DRB1*01:01/EBV EBNA1 (TSLYNLRRGTALA) MHC Monomer | MHC Multimer | |
| MHC-YF072 | DRB1*07:01/EBV EBNA1 (VYGGSKTSLYNLRRGTALAI) MHC Monomer | MHC Multimer | |
| MHC-YF073 | DRB1*07:01/EBV EBNA1 (PGPLRESIVCYFMVFLQTHI) MHC Monomer | MHC Multimer | |
| MHC-YF177 | B*35:01/EBV EBNA1 (HPVGEADYFEY) MHC Monomer | MHC Multimer | |
| MHC-YF403 | B*35:01/EBV EBNA-1 (4A) (HPVAEADYFEY) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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