DRB1*04:01/Human PSMA (NYTLRVDCTPLMYSL) MHC Tetramer
CAT#: MHC-YF886
This product is a MHC tetramer of biotinylated peptide/MHC complex composed PSMA-derived peptide of NYTLRVDCTPLMYSL sequence covering 459-473 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- PSMA
- Antigen Species
- Human
- Peptide
- NYTLRVDCTPLMYSL
- Range
- 459-473
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
- Alternative Names
- PSM; FGCP; FOLH; GCP2; PSMA; mGCP; GCPII; NAALAD1; NAALAdase
- Gene ID
- 2346
- UniProt ID
- Q04609
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|---|---|---|---|
| HPAB-1029LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1029LY-S(P)) | ELISA | Human scfv |
| HPAB-1030LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1030LY-S(P)) | ELISA | Human scfv |
| HPAB-1031LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1031LY-S(P)) | ELISA | Human scfv |
| HPAB-1032LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1032LY-S(P)) | ELISA | Human scfv |
| HPAB-1033LY-S(P) | Human Anti-PSMA Recombinant Antibody; scFv Fragment (HPAB-1033LY-S(P)) | ELISA | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1029LY | Human Anti-PSMA Recombinant Antibody (HPAB-1029LY) | ELISA | Human IgG |
| HPAB-1030LY | Human Anti-PSMA Recombinant Antibody (HPAB-1030LY) | ELISA | Human IgG |
| HPAB-1031LY | Human Anti-PSMA Recombinant Antibody (HPAB-1031LY) | ELISA | Human IgG |
| HPAB-1032LY | Human Anti-PSMA Recombinant Antibody (HPAB-1032LY) | ELISA | Human IgG |
| HPAB-1033LY | Human Anti-PSMA Recombinant Antibody (HPAB-1033LY) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1029LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1029LY-F(E)) | ELISA | Human Fab |
| HPAB-1030LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1030LY-F(E)) | ELISA | Human Fab |
| HPAB-1031LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1031LY-F(E)) | ELISA | Human Fab |
| HPAB-1032LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1032LY-F(E)) | ELISA | Human Fab |
| HPAB-1033LY-F(E) | Human Anti-PSMA Recombinant Antibody; Fab Fragment (HPAB-1033LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY102 | Human Anti-PSMA scFv-Fc Chimera (VS-0125-FY102) | BI | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1774 | Anti-PSMA Immunohistochemistry Kit | IHC |
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