DRB1*15:01/Mycobacterium tuberculosis Mtb ESAT-6 like protein (MSQIMYNYPAMMAHA) MHC Monomer (CAT#: MHC-YF125)
This product is a MHC monomer of biotinylated peptide/MHC complex composed Mtb ESAT-6 like protein-derived peptide of MSQIMYNYPAMMAHA sequence and DRB1*15:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Specifications
- Allele
- DRB1*15:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- Mtb ESAT-6 like protein
- Antigen Species
- Mycobacterium tuberculosis
- Peptide
- MSQIMYNYPAMMAHA
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- A secreted protein that plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. Acts as a strong host (human) T-cell antigen. Inhibits IL-12 p40 (IL12B) and TNF-alpha expression by infected host (mouse) macrophages, reduces the nitric oxide response by about 75%.
- Alternative Names
- 6 kDa early secretory antigenic target; ESAT-6; esxA; esaT6; Rv3875; MTV027.10
- Gene ID
- 886209
- UniProt ID
- P9WNK7
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-276CQ | Recombinant Mouse Anti-M. tuberculosis ESAT6 Antibody | ELISA | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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