H-2 IAd/Mouse Murine class II-associated invariant chain peptide (CLIP) (PVSQMRMATPLLMRP) MHC Tetramer
CAT#: MHC-YF903
This product is a MHC tetramer of biotinylated peptide/MHC complex composed Murine class II-associated invariant chain peptide (CLIP)-derived peptide of PVSQMRMATPLLMRP sequence covering 86-100 and H-2 IAd molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2 IAd
- Class
- Class II
- MHC Species
- Mouse
- Antigen
- Murine class II-associated invariant chain peptide (CLIP)
- Antigen Species
- Human
- Peptide
- PVSQMRMATPLLMRP
- Range
- 86-100
- Application
- FCM
Target
- Antigen Introduction
- The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.
- Alternative Names
- CLIP1; CAP-Gly domain containing linker protein 1; RSN; CLIP; CYLN1; CLIP170; CLIP-170
- Gene ID
- 6249
- UniProt ID
- P30622
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Excellent Negative Control
This H-2 IAd CLIP tetramer served as a perfect negative control for our experiments. It is loaded with the invariant chain peptide PVSQMRMATPLLMRP, allowing us to establish background levels for our antigen-specific assays.
Reliable Control Reagent
Using this CLIP tetramer helped validate our specific staining results. The complex covering amino acids 86-100 behaved consistently, ensuring that the signals we saw with our test tetramers were genuine antigen-specific events.
Q&As
-
What is the purpose of this CLIP tetramer?
A: This tetramer loaded with the CLIP peptide (PVSQMRMATPLLMRP) is typically used as a negative control in MHC Class II tetramer staining experiments. It helps determine background binding levels.
-
What is the MHC allele and species for this product?
A: This product uses the mouse H-2 IAd MHC Class II allele. It is designed for use in mouse T cell research, specifically for analyzing CD4 T cell populations in flow cytometry.
View the frequently asked questions answered by Creative Biolabs Support.
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Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "Murine class II-associated invariant chain peptide (CLIP)"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF902 | H-2 IAb/Mouse Murine class II-associated invariant chain peptide (CLIP) (PVSQMRMATPLLMRP) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF904 | H-2 IAg7/Mouse Murine class II-associated invariant chain peptide (CLIP) (PVSQMRMATPLLMRP) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF1054 | APC-H-2 IAb/Mouse Murine class II-associated invariant chain peptide (CLIP) (PVSQMRMATPLLMRP) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF1055 | APC-H-2 IAd/Mouse Murine class II-associated invariant chain peptide (CLIP) (PVSQMRMATPLLMRP) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF1056 | APC-H-2 IAg7/Mouse Murine class II-associated invariant chain peptide (CLIP) (PVSQMRMATPLLMRP) MHC Tetramer | FCM |
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