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    Recombinant Human Anti-AKAP13 Soluble TCR (H21) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF1372)

    Human TCR (H21) recognizes AKAP13 peptide (KLMNIQQQL) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (H21). Please note that the activity is not guaranteed.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human gallbladder
    Figure 2 IHC staining of human gallbladder
    (Immunohistochemical staining of human gallbladder shows cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_A_6_4_selected.jpg
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_B_8_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_A_7_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_A_6_6.jpg
    Figure 8 Heart muscle
    Figure 8 Heart muscle
    (Cardiomyocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_B_6_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/19773/45435_A_7_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (HMC-1)
    Figure 10 RNA cell line category: Cell line enhanced (HMC-1)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000170776-AKAP13

    Specifications

    • Host Species
    • Human
    • Target
    • AKAP13
    • Species Reactivity
    • Human
    • Epitope
    • KLMNIQQQL
    • MHC
    • HLA-A2
    • Clone
    • H21
    • Type
    • Soluble TCR (ZIP-Fos/ZIP-Jun)
    • TCR Expression Strategy
    • ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

    Target

    • Alternative Names
    • A-Kinase Anchoring Protein 13; Lymphoid Blast Crisis Oncogene; Breast Cancer Nuclear Receptor-Binding Auxiliary Protein; Non-Oncogenic Rho GTPase-Specific GTP Exchange Factor; Guanine Nucleotide Exchange Factor Lbc; Protein Kinase A-Anchoring Protein 13; Human Thyroid-Anchoring Protein 31; A Kinase (PRKA) Anchor Protein 13; LBC Oncogene; AKAP-Lbc; AKAP-13; PRKA13;

    Related Resources

    • Related Signaling Pathways

    Downloads

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    See other products for "Clone H21"

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    IgG Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    MOB-0558MZ Mouse Anti-AKAP13 Recombinant Antibody (clone CBLS-082) WB Mouse IgG2a
    VS3-WK907 Mouse Anti-AKAP13 Recombinant Antibody (VS3-WK907) WB Mouse IgG

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