Recombinant Human Anti-CRYAB Soluble TCR (C-Cys) (VS-0622-YF4316) (CAT#: VS-0622-YF4316)
Human TCR recognizes CRYAB peptide (ITREEKPAVTAAPKK) in the context of HLA-DRB1*15:01. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2053/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2053/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40560/385_H1_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40560/385_H1_1_selected.jpg
Figure 3 Skeletal muscle
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_2_6_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_2_6_val_selected.jpg
Figure 4 Kidney
(Bowman's capsule Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167453_A_9_5.jpg
(Bowman's capsule Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167453_A_9_5.jpg
Figure 5 Cerebral cortex
(Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_9_5.jpg
(Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_9_5.jpg
Figure 6 RNA cell line category: Group enriched (ASC diff, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109846-CRYAB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109846-CRYAB
Specifications
- Host Species
- Human
- Target
- CRYAB
- Species Reactivity
- Human
- Epitope
- ITREEKPAVTAAPKK
- MHC
- HLA-DRB1*15:01
- Type
- Soluble TCR (C-Cys)
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Crystallin Alpha B; Renal Carcinoma Antigen NY-REN-27; Heat Shock Protein Beta-5; Rosenthal Fiber Component; CRYA2; HSPB5; Epididymis Secretory Protein Li 101; Heat-Shock 20 KD Like-Protein; Alpha-Crystallin B Chain;
- Gene ID
- 1410
- UniProt ID
- P02511
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Rabbit Monoclonal Antibodies
IgG Antibodies
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0818 | Hi-Affi™ Rabbit Anti-CRYAB Recombinant Antibody (clone DS818AB) | ICC, IHC-P, WB | Rabbit IgG |
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