Recombinant Human Anti-CRYAB Soluble TCR (C-Cys) (VS-0622-YF4316) (CAT#: VS-0622-YF4316)
Human TCR recognizes CRYAB peptide (ITREEKPAVTAAPKK) in the context of HLA-DRB1*15:01. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2053/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2053/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40560/385_H1_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40560/385_H1_1_selected.jpg
Figure 3 Skeletal muscle
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_2_6_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_2_6_val_selected.jpg
Figure 4 Kidney
(Bowman's capsule Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167453_A_9_5.jpg
(Bowman's capsule Staining: High Intensity: Strong Quantity: 75%-25% Distal tubules Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167453_A_9_5.jpg
Figure 5 Cerebral cortex
(Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_9_5.jpg
(Glial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57100/167428_B_9_5.jpg
Figure 6 RNA cell line category: Group enriched (ASC diff, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109846-CRYAB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000109846-CRYAB
Specifications
- Host Species
- Human
- Target
- CRYAB
- Species Reactivity
- Human
- Epitope
- ITREEKPAVTAAPKK
- MHC
- HLA-DRB1*15:01
- Type
- Soluble TCR (C-Cys)
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Crystallin Alpha B; Renal Carcinoma Antigen NY-REN-27; Heat Shock Protein Beta-5; Rosenthal Fiber Component; CRYA2; HSPB5; Epididymis Secretory Protein Li 101; Heat-Shock 20 KD Like-Protein; Alpha-Crystallin B Chain;
- Gene ID
- 1410
- UniProt ID
- P02511
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1810z | Mouse Anti-CRYAB Recombinant Antibody (clone 18F7) | WB, FC, ICC, IF, IHC, IP | Mouse IgG1 |
| MRO-0065-CN | Rabbit Anti-CRYAB Recombinant Antibody (clone JA50-32) | WB, IHC, IF, IP | Rabbit IgG |
| VS3-QX282 | Mouse Anti-CRYAB Recombinant Antibody (clone 1329CT523.140.120) | WB | Mouse IgG1, κ |
| VS3-XY532 | Mouse Anti-CRYAB Recombinant Antibody (clone 1D11C6E6) | ELISA, WB, IHC | Mouse IgG2a |
| VS3-FY415 | Recombinant Rabbit Anti-CRYAB Antibody (clone R02-7A2) | WB, ICC, IF, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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