


CRYAB

Anti-CRYAB Products
- Rabbit Anti-CRYAB Recombinant Antibody (clone JA50-32) (MRO-0065-CN)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC, IF, IP
- Human Anti-CRYAB Recombinant Soluble TCR (clone A7) (scTCR-0307YC-S(P))
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- Species Reactivity: Human
- Epitope: ITREEKPAVTAAPKK
- MHC: HLA-DRB1*15:01
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- Species Reactivity: E. coli, Human
- Type: Mouse IgG
- Application: WB, IHC, ELISA
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- Species Reactivity: Human
- Epitope: ITREEKPAVTAAPKK
- MHC: HLA-DRB1*15:01
- Recombinant Human Anti-CRYAB Soluble TCR (C-Cys) (VS-0622-YF4316) (VS-0622-YF4316)
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- Species Reactivity: Human
- Epitope: ITREEKPAVTAAPKK
- MHC: HLA-DRB1*15:01
- Recombinant Human Anti-CRYAB Soluble TCR (KIH) (VS-0622-YF7024) (VS-0622-YF7024)
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- Species Reactivity: Human
- Epitope: ITREEKPAVTAAPKK
- MHC: HLA-DRB1*15:01
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1, κ
- Application: WB
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, WB, IHC
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, ICC, IF, IHC, IP
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC-p, IF, ELISA
- Anti-CRYAB Immunohistochemistry Kit (VS-0325-XY555)
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- Species Reactivity: Human, Mouse, Rat
- Target: CRYAB
- Application: IHC
- Rabbit Anti-CRYAB Recombinant Antibody (VS13-YC253) (VS13-YC253)
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- Species Reactivity: Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P
- Anti-Rat CRYAB Immunohistochemistry Kit (VS-0525-XY1691)
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- Species Reactivity: Human, Rat, Bovine
- Target: CRYAB
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Cancer-related genes, Disease related genes, Human disease related genes
Intracellular, Membrane (different isoforms)
Cell type enhanced (Proximal tubular cells, Cardiomyocytes, Basal prostatic cells, Muller glia cells)
Not detected in immune cells
Group enriched (ASC diff, fHDF/TERT166)
Heteromer composed of three CRYAA and one CRYAB subunits (PubMed:20836128). Aggregates with homologous proteins, including the small heat shock protein HSPB1, to form large heteromeric complexes (PubMed:10751411). Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens (PubMed:22890888). Interacts with HSPBAP1 and TTN/titin (PubMed:14676215). Interacts with TMEM109 (PubMed:23542032). Interacts with DES; binds rapidly during early stages of DES filament assembly and a reduced binding seen in the later stages (PubMed:28470624). Interacts with TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion (PubMed:32272059). Interacts with ATP6V1A and with MTOR, forming a ternary complex (PubMed:31786107).
Chaperone, Eye lens protein