Human Anti-hly scFv-Fc Chimera (VS-0125-FY97) (CAT#: VS-0125-FY97)
This product has developed a new therapeutic strategy targeting the α-hemolysin of Staphylococcus aureus, utilizing HEK293F cells to express an IgG-like scFv-Fc for enhanced stability and functionality. Functional validation shows that this antibody can effectively protect cells and has the ability to neutralize α-hemolysin, indicating its potential in combating bacterial toxins. The research findings provide a novel preventive method against MRSA infections, establishing both a theoretical foundation and experimental evidence. The development of this antibody offers new ideas and directions for the treatment of MRSA-related infections, aiming to alleviate the treatment challenges posed by such infections. Overall, this innovative antibody has broad application prospects in improving infection control strategies.
Specific Inquiry
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Species Reactivity
- S. aureus
- Applications
- Neutralization
- Related Disease
- MRSA infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The functional validation of scFv-Fc shows that it can effectively neutralize the toxicity of α-hemolysin.
Target
- Alternative Names
- Alpha-hemolysin, α-Hemolysin, α-Toxin, Hla, Staphylococcal α-hemolysin
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-301-MZ | Mouse Anti-HLY Recombinant Antibody (clone 3) | ELISA, WB | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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