Recombinant Human Anti-LCP1 Soluble TCR (JH2) (C-Cys) (CAT#: VS-0622-YF3991)
Human TCR (JH2) recognizes LCP1 peptide (NLFNRYPAL) in the context of HLA class I. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/20673/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/20673/if_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/277_F2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/277_F2_1_blue_red_green.jpg
Figure 4 Colon
(Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_8_3.jpg
(Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_8_3.jpg
Figure 5 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_9_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, HL-60, HMC-1, JURKAT, NB-4, THP-1, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136167-LCP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136167-LCP1
Specifications
- Host Species
- Human
- Target
- LCP1
- Species Reactivity
- Human
- Epitope
- NLFNRYPAL
- MHC
- HLA class I
- Clone
- JH2
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Breast cancer
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-801-sdAb | Recombinant Anti-human LCP1 VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
| TAB-0071CL-VHH | Anti-Human LCP1 VHH Single Domain Antibody (TAB-0071CL-VHH) | ELISA, FC | Single domain antibody |
| TAB-0072CL-VHH | Anti-Human LCP1 VHH Single Domain Antibody (TAB-0072CL-VHH) | ELISA, FC | Single domain antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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