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LCP1

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Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

Derivation:
Camelid
Species Reactivity:
Human
Type:
Antibody
Derivation:
Camelid
Species Reactivity:
Human
Type:
ADCC enhanced antibody
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
IP, IF, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, IP, FuncS
Species Reactivity:
Human
Application:
ICC/IF, IHC-Fr, IP, WB
Species Reactivity:
Human
Type:
Llama VHH
Application:
WB, IP, ICC, FC, FA
Derivation:
Phage display library
Type:
Single domain antibody
Application:
ELISA, FC
Derivation:
Phage display library
Type:
Single domain antibody
Application:
ELISA, FC
Derivation:
Phage display library screening
Species Reactivity:
Human
Type:
IgG
Application:
FC, ICC, IHC-P, IP, WB
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