Human Anti-LDL scFv-Fc Chimera (VS-0425-FY44)
CAT#: VS-0425-FY44
The anti-LDL scFv-Fc is an innovative biopharmaceutical designed to specifically bind and neutralize low-density lipoprotein (LDL) cholesterol in the bloodstream. This single-chain variable fragment (scFv) fused to the Fc region of an antibody increases its serum stability and prolongs its biological activity. By targeting LDL, this product aims to reduce cholesterol levels and mitigate the risk of cardiovascular diseases, including atherosclerosis and heart attacks. The anti-LDL scFv-Fc provides a novel approach to cholesterol management, offering potential advantages over traditional statin therapies. in vitro and in vivo studies have demonstrated its efficacy in lowering LDL cholesterol and improving lipid profiles without extensive side effects. This product holds promise as a safer, targeted alternative for patients struggling with hyperlipidemia and cardiovascular health issues.
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human LDL
- Species Reactivity
- Human, Rabbit
- Applications
- Immunoassay
- Related Disease
- Heart disease and stroke
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Low-density lipoprotein; LDL; Ldl cholesterol
- Long Name
- Low-density lipoprotein
- Function
- The term "LDL" refers to low-density lipoprotein, which is not a gene but a type of lipoprotein particle that circulates in the blood. However, the LDLR gene is critically important for LDL function.
The LDLR gene provides instructions for making the low-density lipoprotein receptor (LDLR) protein. These receptors are primarily located on the surface of liver cells and other tissues. Their main function is to bind to LDL particles in the bloodstream and facilitate their uptake into cells through a process called receptor-mediated endocytosis.
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Related Diseases
Cushing Syndrome
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "LDL"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-615 | Recombinant Anti-LDL Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-615 | Recombinant Human Anti-LDL Antibody | ELISA, WB, FuncS | IgG |
| FAMAB-0056JF | Human Anti-LDL Recombinant Antibody (clone IK17) | WB, ELISA, IHC, Inhib | Human IgG |
| FAMAB-0185JF | Mouse Anti-LDL Recombinant Antibody (clone 1H11) | WB, ELISA, IHC, IF | Mouse IgG |
| FAMAB-0186JF | Mouse Anti-LDL Recombinant Antibody (clone 4E4) | WB, ELISA, IHC, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-615-F(E) | Recombinant Anti-LDL Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| HPAB-1067WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (IEIA8) | ELISA | Human Fab |
| HPAB-1068WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (IEI-E3) | ELISA | Human Fab |
| HPAB-1069WJ-F(E) | Recombinant Human Anti-LDL Antibody Fab Fragment (KTT-D6) | ELISA | Human Fab |
| FAMAB-0185JF-F(E) | Mouse Anti-LDL Recombinant Antibody (clone 1H11); Fab Fragment | ICC, WB, ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-615-S(P) | Recombinant Anti-LDL Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-615-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-1067WJ-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment (IEIA8) | ELISA | Human scFv |
| HPAB-1068WJ-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment (IEI-E3) | ELISA | Human scFv |
| HPAB-1069WJ-S(P) | Recombinant Human Anti-LDL Antibody scFv Fragment (KTT-D6) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0322MZ | Chicken Anti-LDL Polyclonal IgY | Anti-LDL antibody produced in chicken is suitable for indirect ELISA and WBting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200 | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4301 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI390DS) | FC | IgG |
| MOR-4302 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI391DS) | FC | IgG |
| MOR-4303 | Hi-Affi™ Recombinant Rabbit Anti-LDL Monoclonal Antibody (SI392DS) | FC | IgG |
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