Human Anti-LDL scFv-Fc Chimera (VS-0425-FY44) (CAT#: VS-0425-FY44)
The anti-LDL scFv-Fc is an innovative biopharmaceutical designed to specifically bind and neutralize low-density lipoprotein (LDL) cholesterol in the bloodstream. This single-chain variable fragment (scFv) fused to the Fc region of an antibody increases its serum stability and prolongs its biological activity. By targeting LDL, this product aims to reduce cholesterol levels and mitigate the risk of cardiovascular diseases, including atherosclerosis and heart attacks. The anti-LDL scFv-Fc provides a novel approach to cholesterol management, offering potential advantages over traditional statin therapies. in vitro and in vivo studies have demonstrated its efficacy in lowering LDL cholesterol and improving lipid profiles without extensive side effects. This product holds promise as a safer, targeted alternative for patients struggling with hyperlipidemia and cardiovascular health issues.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human LDL
- Species Reactivity
- Human, Rabbit
- Applications
- Immunoassay
- Related Disease
- Heart disease and stroke
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- Low-density lipoprotein; LDL; Ldl cholesterol
- Long Name
- Low-density lipoprotein
- Function
- The term "LDL" refers to low-density lipoprotein, which is not a gene but a type of lipoprotein particle that circulates in the blood. However, the LDLR gene is critically important for LDL function.
The LDLR gene provides instructions for making the low-density lipoprotein receptor (LDLR) protein. These receptors are primarily located on the surface of liver cells and other tissues. Their main function is to bind to LDL particles in the bloodstream and facilitate their uptake into cells through a process called receptor-mediated endocytosis.
Related Resources
Cushing Syndrome
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "LDL"
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Chicken IgY Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-615 | Recombinant Anti-LDL Antibody | ELISA, WB, FC, FuncS | IgG |
| HPAB-1067WJ | Recombinant Human Anti-LDL Antibody (IEIA8) | ELISA | Human IgG |
| HPAB-1068WJ | Recombinant Human Anti-LDL Antibody (IEI-E3) | ELISA | Human IgG |
| HPAB-1069WJ | Recombinant Human Anti-LDL Antibody (KTT-D6) | ELISA | Human IgG |
| FAMAB-0056JF | Human Anti-LDL Recombinant Antibody (clone IK17) | WB, ELISA, IHC, Inhib | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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