Human Anti-THSD7A scFv-Fc Chimera (VS-0325-FY149) (CAT#: VS-0325-FY149)
An anti-THSD7A scFv-Fc antibody is an antibody that binds to the thrombospondin type-1 domain-containing 7A (THSD7A) protein. The scFv-Fc format is a recombinant antibody that combines the antigen-binding of an scFv with the effector functions of an Fc. Anti-THSD7A antibodies can be used to detect autoantibodies against THSD7A.
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Custom Production
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Specifications
- Immunogen
- Recombinant human-derived THSD7A protein, expressed by HEK293, with C-His labeled tag.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human THSD7A
- Species Reactivity
- Human
- Applications
- Immunoassay
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Thrombospondin Type 1 Domain Containing 7A; KIAA0960
- Gene ID
- 221981
- UniProt ID
- Q9UPZ6
- Long Name
- Thrombospondin Type 1 Domain Containing 7A
- Cellular Localization
- Cell membrane; Cell projection
- Post Translation Modifications
- Proteolytic cleavage in the extracellular region generates a 210 kDa soluble form.
Extensively N-glycosylated.
Glycosylation at Asn234, Asn332, Asn450, Asn500, Asn679, Asn717, Asn968, Asn1043, Asn1182, Asn1225, Asn1276, Asn1366, Asn1500, and Asn1547
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 15 sites, 24 N-linked glycans (5 sites), 1 O-linked glycan (1 site)
- Protein Refseq
- XP_006715722.1; XP_006715723.1; XP_006715725.1; XP_047275995.1; XP_047275996.1
- Function
- THSD7A (Thrombospondin type 1 domain containing 7A) is a cell surface protein involved in angiogenesis and cell adhesion. It plays a role in kidney diseases, and also in some forms of cancer.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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