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    Recombinant Human Anti-TRPV4 Soluble TCR (BF4) (KIH) (CAT#: VS-0622-YF7899)

    Human TCR (BF4) recognizes TRPV4 peptide (FMIGYASAL) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_B_7_5.jpg
    Figure 2 Pancreas
    Figure 2 Pancreas
    (Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_A_2_3.jpg
    Figure 3 Testis
    Figure 3 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_A_5_6.jpg
    Figure 4 Lymph node
    Figure 4 Lymph node
    (Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_A_9_8.jpg
    RNA Expression
    Figure 5 RNA cell line category: Cell line enhanced (BEWO, BJ hTERT+, EFO-21, HaCaT, HUVEC TERT2)
    Figure 5 RNA cell line category: Cell line enhanced (BEWO, BJ hTERT+, EFO-21, HaCaT, HUVEC TERT2)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111199-TRPV4

    Specifications

    • Host Species
    • Human
    • Target
    • TRPV4
    • Species Reactivity
    • Human
    • Epitope
    • FMIGYASAL
    • MHC
    • HLA-A2
    • Clone
    • BF4
    • Type
    • Soluble TCR (KIH)
    • TCR Expression Strategy
    • KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).

    Target

    • Alternative Names
    • Transient Receptor Potential Cation Channel Subfamily V Member 4; Osmosensitive Transient Receptor Potential Channel 4; Transient Receptor Potential Protein 12; Vanilloid Receptor-Like Channel 2; Osm-9-Like TRP Channel 4; OTRPC4; TRP12; VROAC; VRL2; Transient Receptor Potential Cation Channel, Subfamily V, Member 4; Vanilloid Receptor-Related Osmotically Activated Channel; Vanilloid Receptor-Related Osmotically-Activated Channel

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