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TRPV4
Loading...Anti-TRPV4 Recombinant Antibody Products
- Human Anti-TRPV4 Recombinant Soluble TCR (clone AD6) (scTCR-1191YC-S(P))
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone AH5) (scTCR-1192YC-S(P))
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone BD4) (scTCR-1193YC-S(P))
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone BF4) (scTCR-1194YC-S(P))
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
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- Human Anti-TRPV4 Recombinant Soluble TCR (clone FA11) (scTCR-1195YC-S(P))
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
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- Human Anti-TRPV4 Recombinant Soluble TCR (clone FF4) (scTCR-1196YC-S(P))
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
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- Recombinant Human Anti-TRPV4 Soluble TCR (FG2) (KIH) (VS-0622-YF7903)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (GF7) (KIH) (VS-0622-YF7905)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
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- Recombinant Human Anti-TRPV4 Soluble TCR (JG11) (KIH) (VS-0622-YF7906)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
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- Recombinant Human Anti-TRPV4 Soluble TCR (LG2) (KIH) (VS-0622-YF7907)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (AH5) (KIH) (VS-0622-YF7897)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (BD4) (KIH) (VS-0622-YF7898)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (BF4) (KIH) (VS-0622-YF7899)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FA11) (KIH) (VS-0622-YF7900)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FF4) (KIH) (VS-0622-YF7901)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FF7) (KIH) (VS-0622-YF7902)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FF7) (C-Cys) (VS-0622-YF5194)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FG2) (C-Cys) (VS-0622-YF5195)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (GF7) (C-Cys) (VS-0622-YF5197)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (JG11) (C-Cys) (VS-0622-YF5198)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (LG2) (C-Cys) (VS-0622-YF5199)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (AD6) (KIH) (VS-0622-YF7896)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (AD6) (C-Cys) (VS-0622-YF5188)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (AH5) (C-Cys) (VS-0622-YF5189)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (BD4) (C-Cys) (VS-0622-YF5190)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (BF4) (C-Cys) (VS-0622-YF5191)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FA11) (C-Cys) (VS-0622-YF5192)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FF4) (C-Cys) (VS-0622-YF5193)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FF4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2485)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FF7) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2486)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FG2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2487)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (GF7) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2489)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (JG11) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2490)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (LG2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2491)
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone (LG2)-2) (scTCR-1203YC-S(P))
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (AD6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2480)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (AH5) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2481)
-
- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (BD4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2482)
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (BF4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2483)
-
- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Recombinant Human Anti-TRPV4 Soluble TCR (FA11) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2484)
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone FF7) (scTCR-1197YC-S(P))
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone (FG2)-1) (scTCR-1198YC-S(P))
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone (FG2)-2) (scTCR-1199YC-S(P))
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone GF7) (scTCR-1200YC-S(P))
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- Species Reactivity: Human
- Epitope: YLLFMIGYA
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone JG11) (scTCR-1201YC-S(P))
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- Epitope: FMIGYTSAL
- MHC: HLA-A2
Compare
- Human Anti-TRPV4 Recombinant Soluble TCR (clone (LG2)-1) (scTCR-1202YC-S(P))
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- Species Reactivity: Human
- Epitope: FMIGYASAL
- MHC: HLA-A2
Compare
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Voltage-gated ion channels
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Respiratory ciliated cells, Syncytiotrophoblasts, Cytotrophoblasts, Cholangiocytes, Kupffer cells, Basal respiratory cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BEWO, BJ hTERT+, EFO-21, HaCaT, HUVEC TERT2)
Interaction
Homotetramer (Probable). Self-associates in an isoform-specific manner (PubMed:16293632). Isoform 1 and isoform 5 can oligomerize, but isoform 2, isoform 4 and isoform 6 cannot oligomerize (PubMed:16293632). Interacts with calmodulin (PubMed:12724311). Interacts with Map7 and Src family Tyr protein kinases LYN, SRC, FYN, HCK, LCK and YES (By similarity). Interacts with CTNNB1 (By similarity). The TRPV4 and CTNNB1 complex can interact with CDH1 (By similarity). Interacts with PACSIN1, PACSIN2 and PACSIN3 (via SH3 domain) (By similarity). Part of a complex containing MLC1, AQP4, HEPACAM and ATP1B1 (PubMed:22328087). Interacts with ITPR3 (PubMed:18826956). Interacts with AQP5; the interaction is probably indirect and regulates TRPV4 activation by hypotonicity (By similarity). Interacts with ANO1 (By similarity). Interacts (via C-terminus) with PKD2 (via C-terminus) (PubMed:18695040). Interacts with DDX3X; this interaction is decreased when the channel is activated (PubMed:29899501).
Molecular function
Calcium channel, Calmodulin-binding, Ion channel
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