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    Recombinant Human Anti-TRPV4 Soluble TCR (JG11) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2490)

    Human TCR (JG11) recognizes TRPV4 peptide (FMIGYTSAL) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (JG11). Please note that the activity is not guaranteed.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_B_7_5.jpg
    Figure 2 Pancreas
    Figure 2 Pancreas
    (Pancreatic endocrine cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_A_2_3.jpg
    Figure 3 Testis
    Figure 3 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_A_5_6.jpg
    Figure 4 Lymph node
    Figure 4 Lymph node
    (Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7150/20711_A_9_8.jpg
    RNA Expression
    Figure 5 RNA cell line category: Cell line enhanced (BEWO, BJ hTERT+, EFO-21, HaCaT, HUVEC TERT2)
    Figure 5 RNA cell line category: Cell line enhanced (BEWO, BJ hTERT+, EFO-21, HaCaT, HUVEC TERT2)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111199-TRPV4

    Specifications

    • Host Species
    • Human
    • Target
    • TRPV4
    • Epitope
    • FMIGYTSAL
    • MHC
    • HLA-A2
    • Clone
    • JG11
    • Type
    • Soluble TCR (ZIP-Fos/ZIP-Jun)
    • TCR Expression Strategy
    • ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

    Target

    • Alternative Names
    • Transient receptor potential cation channel subfamily V member 3 variant FMI_A6T; FMIGYTSAL

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