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    Recombinant Human Anti-USP28 Soluble TCR (BE2) (KIH) (CAT#: VS-0622-YF8015)

    Human TCR (BE2) recognizes USP28 peptide (LIIPCIHLI) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.

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    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6778/8_E3_1_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6779/18817_B_9_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6778/18642_A_7_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6779/18817_A_8_4.jpg
    Figure 5 Pancreas
    Figure 5 Pancreas
    (Exocrine glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Pancreatic endocrine cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6778/18642_A_2_3.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6779/18817_A_8_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Preleptotene spermatocytes Staining: Medium Intensity: Strong Quantity: <25% Round or early spermatids Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: Medium Intensity: Strong)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6779/18817_A_6_6.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/6778/18642_A_8_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Low cell line specificity
    Figure 9 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000048028-USP28

    Specifications

    • Host Species
    • Human
    • Target
    • USP28
    • Species Reactivity
    • Human
    • Epitope
    • LIIPCIHLI
    • MHC
    • HLA-A2
    • Clone
    • BE2
    • Type
    • Soluble TCR (KIH)
    • Related Disease
    • Cancer
    • TCR Expression Strategy
    • KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).

    Target

    • Alternative Names
    • Ubiquitin Specific Peptidase 28; Ubiquitin-Specific-Processing Protease 28; Ubiquitin Specific Protease 28; Deubiquitinating Enzyme 28; Ubiquitin Thioesterase 28; EC 3.4.19.12; EC 3.1.2.15; KIAA1515

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