IgG-digesting Enzyme B (Yielding F(ab')₂ and Fc) (CAT#: VS-0724-CJ2)

This product is a recombinant protease that digests IgG molecules to homogenous F(ab')₂ and Fc fragments. IgG-digesting enzyme B digests mouse IgG2a/IgG3 and IgG of human, monkey, rabbit and sheep. It does not digest mouse IgG1 and IgG2b. It is recommended to incubate the mouse IgG2a at 37 °C for 2 hours and 1 unit IgG-digesting enzyme B corresponds to 1 µg of mouse IgG2a or IgG3.

Specific Inquiry
  • Datasheet
  • MSDS
  • COA

Specifications

  • Cleavage Site
  • Below the hinge: LLG | GPS (Human IgG1; Mouse IgG2a); ILG | GPS (Mouse IgG3)
  • Species Reactivity
  • Human, Mouse, Monkey, Rabbit, Sheep
  • Specificity
  • Human IgG1-4; Mouse IgG2a and IgG3; Some Classes of monkey, rabbit and sheep
  • Reaction Condition
  • 2-hour reaction; Physiological buffers
  • Format
  • Lyophilized; Immobilized; Kit
  • Original Source
  • S. equi ssp. Zooepidemicus

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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