JAK2-STAT3 Pathway Antibody Panel (JAK2, STAT3)
CAT#: VS-0725-YC2
The JAK2-STAT3 Pathway Antibody Panel are sets of 5 antibodies designed for the simultaneous detection of key total and activated (phosphorylated) proteins in this pathway. Our comprehensive set includes antibodies against JAK2, phosphorylated JAK2 (pTyr 1007 / pTyr 1008), STAT3, and phosphorylated STAT3 (pTyr 705). This panel is an ideal tool for investigating processes like cell growth, differentiation, immune responses, and apoptosis, delivering robust and reproducible results for your studies.
Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
MRO-2341-CN | Recombinant Rabbit Anti-JAK2 (phosphorylated Tyr1007+Tyr1008) Monoclonal Antibody (CBACN-632) | CBACN-632 | Rabbit IgG | JAK2 (Albumin) | Human, Mouse, Rat | Used for immunoassay techniques such as: Western Blot; Immunofluorescence; Immunohistochemistry; Immunoprecipitation | |
ZG-0072U | Rabbit Anti-STAT3 Recombinant Antibody (clone 9F10) | 9F10 | Rabbit IgG | STAT3 | Human | ELISA, IHC | |
ZG-0581U | Rabbit Anti-Phospho-STAT3 (S727) Recombinant Antibody (clone 2A9) | 2A9 | Rabbit IgG | STAT3 | Human | ELISA, WB, IHC, IP | |
ZG-0582U | Rabbit Anti-Phospho-STAT3 (Tyr705) Recombinant Antibody (clone 3D11) | 3D11 | Rabbit IgG | STAT3 | Human | ELISA, WB, IHC | |
VS3-CJ157 | Rabbit Anti-JAK2 Recombinant Antibody (VS3-CJ157) | Rabbit IgG | JAK2 | Human, Mouse, Rat | WB, ICC, IHC, IP |
Specifications
- Targets
- JAK2, JAK2 (pTyr 1007 / pTyr 1008), STAT3, STAT3 (pTyr 705)
- Species Reactivity
- Human
- Research Area
- JAK2/STAT3 signaling pathway
- Introduction
- The JAK2/STAT3 signaling pathway is a critical intracellular cascade that primarily transduces signals from cytokines, growth factors, and hormones, profoundly influencing cellular processes such as proliferation, differentiation, survival, and immune responses. At its core, the pathway involves Janus Kinases (JAKs), a family of cytoplasmic tyrosine kinases, and Signal Transducers and Activators of Transcription (STATs), a family of transcription factors.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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Downloadable Resources
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Datasheet
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