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JAK2-STAT3 Pathway

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For Research Use Only. Not For Clinical Use.


Background

The JAK2/STAT3 signaling pathway is a critical intracellular cascade that primarily transduces signals from cytokines, growth factors, and hormones, profoundly influencing cellular processes such as proliferation, differentiation, survival, and immune responses. At its core, the pathway involves Janus Kinases (JAKs), a family of cytoplasmic tyrosine kinases, and Signal Transducers and Activators of Transcription (STATs), a family of transcription factors.
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