M1 and M2 Type TAM Marker Antibody Panel (CD68, CD163, MRC1, NOS2)
CAT#: VS-0725-YC13
The M1 and M2 Type TAM Marker Antibody Panel are sets of 4 antibodies, allowing for the simultaneous detection of crucial markers that define M1 and M2 macrophage populations. Our comprehensive set includes antibodies against CD68, CD163, MRC1, and NOS2. This panel serves as an invaluable tool for oncology research, enabling a clearer understanding of the tumor microenvironment and its impact on disease progression and therapeutic response.
| Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
| TAB-0828CL | Anti-Human MRC1 Recombinant Antibody (B11) | B11 | Human antibody | MMR (macrophage mannose receptor) | ELISA | ||
| VS3-QX195 | Mouse Anti-CD68 Recombinant Antibody (clone 8A5D12) | 8A5D12 | Mouse IgG1 | CD68 | Human | WB, IHC, ICC, FC, ELISA | |
| NS-044CN | Human Anti-NOS2 Recombinant Antibody (clone 1E8-B8) | 1E8-B8 | Human IgG1, κ | NOS2 | Human | ELISA, FC | |
| VS4-WK77 | Mouse Anti-CD163 Recombinant Antibody (VS4-WK77) | Mouse IgG1, Kappa | CD163 | Human | ELISA, IHC |
More Infomation
Specifications
- Targets
- CD68, CD163, MRC1, NOS2
- Species Reactivity
- Human
- Research Area
- M1 and M2 TAM Marker
- Introduction
- Macrophages are remarkably plastic immune cells that adapt their phenotype and function in response to diverse microenvironmental cues. Within the context of cancer, these cells often infiltrate tumors and differentiate into Tumor-Associated Macrophages (TAMs), which are major players in shaping the tumor microenvironment (TME) and influencing disease progression. Traditionally, TAMs are broadly categorized into two main functional subtypes, M1 and M2, representing opposite ends of a polarization spectrum, though it's increasingly recognized that macrophages exhibit a more complex continuum of activation states in vivo
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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