Polycomb Complex Antibody Panel (EZH2, HIST1H3A, RING1, RNF2)
CAT#: VS-0725-YC57
The Polycomb Complex Antibody Panel are sets of 4 antibodies, enabling the simultaneous detection of key components of Polycomb Repressive Complexes. Our comprehensive set includes antibodies against EZH2, HIST1H3A, RING1, and RNF2. This panel streamlines your research into development, stem cell biology, and cancer epigenetics, consistently delivering robust and reproducible results for your mechanistic studies.
Sub Cat | Component Name | Clone | Type | Target | Species Reactivity | Applications | |
VS3-QX973 | Mouse Anti-RING1 Recombinant Antibody (clone 7D12-G1-B7) | 7D12-G1-B7 | Mouse IgG1 | RING1 | Human | WB, IHC, ICC, FC, ELISA | |
VS3-QX394 | Mouse Anti-EZH2 Recombinant Antibody (clone 3D2A4) | 3D2A4 | Mouse IgG1 | EZH2 | Human | WB, IHC, ICC, FC, ELISA | |
VS3-WK293 | Rabbit Anti-RNF2 Recombinant Antibody (clone JB38-41) | JB38-41 | Rabbit IgG | RNF2 | Human, Mouse, Rat | WB, ELISA | |
VS3-QX526 | Mouse Anti-HIST1H3A Recombinant Antibody (clone 3B8-7G7-4E5) | 3B8-7G7-4E5 | Mouse IgG1 | HIST1H3A | Human, Rat, Mouse | WB, IHC |
Specifications
- Targets
- EZH2, HIST1H3A, RING1, RNF2
- Species Reactivity
- Human
- Research Area
- Polycomb Complexes
- Introduction
- Polycomb Group (PcG) complexes are highly conserved, multi-protein epigenetic regulators that play a crucial role in gene silencing and maintaining cell identity throughout development, from early embryogenesis to adult tissue homeostasis. They operate by modifying chromatin structure, thereby ensuring that genes that should remain "off" in specific cell types or developmental stages stay repressed, even after the initial developmental cues have faded. This stable, heritable gene silencing is critical for proper cell differentiation and tissue development.
- Storage
- Store at 4°C for up to a week. For long-term storage, store at -20°C or below.
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Downloadable Resources
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Datasheet
MSDS
COA
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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