Rabbit Anti-MLKL (phospho S358) Monoclonal Antibody
CAT#: VS-0126-XL229
Specifically identifying the activated S358 residue of human MLKL, this rabbit monoclonal acts as a critical indicator of necroptosis. It is an ideal laboratory tool for tissue-based research in WB and IHC.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HUVEC TERT2
Immunofluorescent staining of human cell line HUVEC TERT2 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78638/1751_F6_8_cr57fd37317cd94_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000168404-MLKL
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Specifications
- Host Species
- Rabbit
- Antibody Isotype
- Rabbit IgG
- Specificity
- MLKL (phospho S358)
- Species Reactivity
- Human
- Applications
- WB; IHC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Obtained by implementing a robust biochemical separation protocol that guarantees the high structural integrity of the final purified solution.
- Concentration
- Lot specific
- Storage
- Store at -20˚C
- Shipping
- Ice Packs
Applications
- Application Notes
- WB: 1:500-1:2000
IHC: 1:50-1:200
Target
- Alternative Names
- Mixed lineage kinase domain-like protein (Human-specific phosphorylation site)
- UniProt ID
- Q8NB16
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MLKL"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1006-CN | Recombinant Rabbit Anti-MLKL Monoclonal Antibody (CBACN-374) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2347-CN | Recombinant Rabbit Anti-MLKL (phosphorylated Ser345) Monoclonal Antibody (JM92-37) | WB, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0074-FY | Rabbit Anti-MLKL Recombinant Antibody (clone AFY0045) | IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0106F | Mouse Anti-MLKL Recombinant Antibody (clone 8H7) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0181F | Mouse Anti-MLKL Recombinant Antibody (clone 6F8) | IF, IHC-P | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0182F | Mouse Anti-MLKL Recombinant Antibody (clone 6B4) | IHC-P, IF | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1350 | Anti-MLKL Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4421 | Anti-Human MLKL Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0126-XL26 | Mouse Anti-phospho-MLKL (S358) Monoclonal Antibody (MCB-P0812) | Phospho Antibodies for Cell Signaling Research |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0126-XL116 | Rabbit Anti-MLKL (phospho S345) Monoclonal Antibody | Phospho Antibodies for Cell Signaling Research |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0126-XL241 | Rabbit Anti-MLKL (phospho S345) Monoclonal Antibody (RCB-P0849) | Phospho Antibodies for Cell Signaling Research |
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