Recombinant Anti-ACKR3 Vesicular Antibody, EV Displayed (VS-0425-YC227) (CAT#: VS-0425-YC227)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ACKR3

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Atypical chemokine receptor 3

• Biological Process
• Cell adhesion, Host-virus interaction

• Molecular Function
• Developmental protein, G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Vesicles, Plasma membrane

• Introduction
• This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be a receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.

• Alternative Names
• CMKOR1, CXCR7, GPR159, RDC1

• Gene ID
• 57007

• UniProt ID
• P25106

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