Recombinant Anti-ACKR3 Vesicular Antibody, EV Displayed (VS-0425-YC227)
CAT#: VS-0425-YC227
The Recombinant Anti-ACKR3 Vesicular Antibody, EV Displayed (VS-0425-YC227) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ACKR3-expressed cells or tissues. The ACKR3 is a receptor in the G-protein coupled receptor family. It acts as a coreceptor for HIV, involved in lipoma translocations.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32003/1048_F7_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows cytoplasmic positivity in trophoblasts.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_2_7_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32003/1047_F7_1_blue_red_green.jpg
Normal Tissue
Figure 4 Pancreas
Exocrine glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_1_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49718/116961_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HeLa, MCF7, RT4, SiHa, U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144476-ACKR3
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ACKR3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Atypical chemokine receptor 3
- Biological Process
- Cell adhesion, Host-virus interaction
- Molecular Function
- Developmental protein, G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles, Plasma membrane
- Introduction
- This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be a receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
- Alternative Names
- CMKOR1, CXCR7, GPR159, RDC1
- Gene ID
- 57007
- UniProt ID
- P25106
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC227. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ACKR3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-34 | Recombinant Anti-human ACKR3 Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-34 | Recombinant Human Anti-human ACKR3 Antibody | Neut, IF, FuncS | IgG |
| TAB-168MZ | Anti-Human ACKR3 Recombinant Antibody (6G7) | FC | |
| TAB-169MZ | Anti-Human ACKR3 Recombinant Antibody (7A9) | FC | |
| TAB-171MZ | Anti-Human ACKR3 Recombinant Antibody (10D1) | FC, FuncS |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-34-F(E) | Recombinant Anti-human ACKR3 Antibody Fab Fragment | IF, FuncS | Fab |
| MHH-34-F(E) | Recombinant Human Anti-human ACKR3 Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-34-S(P) | Recombinant Anti-human ACKR3 Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-34-S(P) | Recombinant Human Anti-human ACKR3 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-167MZ | Anti-Human ACKR3 Recombinant Antibody (6G2) | FC | |
| TAB-170MZ | Anti-Human ACKR3 Recombinant Antibody (8C1) | FC | |
| TAB-172MZ | Mouse Anti-ACKR3 Recombinant Antibody (TAB-172MZ) | FC | Mouse IgG |
| TAB-173MZ | Mouse Anti-ACKR3 Recombinant Antibody (TAB-173MZ) | FC, FuncS | Mouse IgG |
| TAB-167MZ-S(P) | Anti-Human ACKR3 Recombinant Antibody scFv Fragment (6G2) | FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-005MZ-VHH | Anti-Human ACKR3 Recombinant Antibody (TAB-005MZ-VHH) | FC, IHC | Single domain antibody |
| TAB-006MZ-VHH | Anti-Human ACKR3 Recombinant Antibody (TAB-006MZ-VHH) | FC, IHC | Single domain antibody |
| TAB-007MZ-VHH | Anti-Human ACKR3 Recombinant Antibody (TAB-007MZ-VHH) | FC, IHC | Single domain antibody |
| TAB-008MZ-VHH | Anti-Human ACKR3 Recombinant Antibody (TAB-008MZ-VHH) | FC, IHC | Single domain antibody |
| TAB-009MZ-VHH | Anti-Human ACKR3 Recombinant Antibody (TAB-009MZ-VHH) | FC, IHC | Single domain antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0892 | Hi-Affi™ Rabbit Anti-ACKR3 Recombinant Antibody (clone DS892AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY134 | Mouse Anti-ACKR3 scFv-Fc Chimera (VS-0325-FY134) | FC | Mouse IgG1, scFv-Fc |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
-2.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, FC, IF, WB
Application: Neut, FuncS, IHC, ELISA, FC, Inhib
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
