Recombinant Anti-ACKR4 Vesicular Antibody, EV Displayed (VS-0425-YC584)
CAT#: VS-0425-YC584
The Recombinant Anti-ACKR4 Vesicular Antibody, EV Displayed (VS-0425-YC584) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ACKR4-expressed cells or tissues. ACKR4 is a G protein-coupled receptor for C-C type chemokines, binding dendritic and T cell-activated chemokines.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to mitochondria & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/54926/1658_F5_3_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (BJ hTERT+)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000129048-ACKR4
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ACKR4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human, Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Atypical chemokine receptor 4
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles, Mitochondria
- Introduction
- The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.
- Alternative Names
- CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1
- Gene ID
- 51554
- UniProt ID
- Q9NPB9
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC584. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "ACKR4"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2470z | Mouse Anti-ACKR4 Recombinant Antibody (clone 43G6) | WB, ELISA, IF, IHC, IP | Mouse IgG1, κ |
| HPAB-0294-CN | Mouse Anti-ACKR4 Recombinant Antibody (HPAB-0294-CN) | FC | Mouse IgG2b |
| HPAB-0296-CN | Human Anti-ACKR4 Recombinant Antibody (HPAB-0296-CN) | FC | Chimeric (Mouse/Human) IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0526 | Hi-Affi™ Rabbit Anti-ACKR4 Recombinant Antibody (clone DS526AB) | WB, IP, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0294-CN-S(P) | Mouse Anti-ACKR4 Recombinant Antibody; scFv Fragment (HPAB-0294-CN-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0294-CN-F(E) | Mouse Anti-ACKR4 Recombinant Antibody; Fab Fragment (HPAB-0294-CN-F(E)) | FC | Mouse Fab |
| HPAB-0296-CN-F(E) | Human Anti-ACKR4 Recombinant Antibody; Fab Fragment (HPAB-0296-CN-F(E)) | FC | Chimeric (Mouse/Human) Fab |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IF, IP, Neut, FuncS, ELISA, FC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, Inhib, IP, ELISA
Application: FC, FRET, Internalization
Application: ELISA
-3.jpg)
Application: IB, FC, ELISA, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
