Recombinant Anti-ACKR4 Vesicular Antibody, EV Displayed (VS-0425-YC584) (CAT#: VS-0425-YC584)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• ACKR4

• Host Animal
• Human

• Antibody Isotype
• IgG

• Species Reactivity
• Human, Mouse

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Atypical chemokine receptor 4

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Vesicles, Mitochondria

• Introduction
• The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.

• Alternative Names
• CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1

• Gene ID
• 51554

• UniProt ID
• Q9NPB9

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