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ACKR4
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described.
Protein class
G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Alveolar cells type 1, Fibroblasts, Proximal enterocytes, Respiratory ciliated cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (BJ hTERT+)
Interaction
Forms heteromers with CXCR3. Interacts with ARRB1 and ARRB2.
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IP, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, ELISA, IF, IHC, IP
- Mouse Anti-ACKR4 Recombinant Antibody (HPAB-0294-CN) (HPAB-0294-CN)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC
- Human Anti-ACKR4 Recombinant Antibody (HPAB-0296-CN) (HPAB-0296-CN)
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (Mouse/Human) IgG4
- Application: FC
- Human Anti-ACKR4 Recombinant Antibody; Fab Fragment (HPAB-0296-CN-F(E)) (HPAB-0296-CN-F(E))
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- Derivation: Chimeric (Mouse/Human)
- Species Reactivity: Human, Mouse
- Type: Chimeric (Mouse/Human) Fab
- Application: FC
- Mouse Anti-ACKR4 Recombinant Antibody; Fab Fragment (HPAB-0294-CN-F(E)) (HPAB-0294-CN-F(E))
-
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
- Mouse Anti-ACKR4 Recombinant Antibody; scFv Fragment (HPAB-0294-CN-S(P)) (HPAB-0294-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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For Research Use Only. Not For Clinical Use.