Recombinant Anti-AGTR1 Vesicular Antibody, EV Displayed (VS-0425-YC289)
CAT#: VS-0425-YC289
The Recombinant Anti-AGTR1 Vesicular Antibody, EV Displayed (VS-0425-YC289) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to AGTR1-expressed cells or tissues. The AGTR1 is the primary receptor for angiotensin II, which mediates cardiovascular effects like blood pressure regulation.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line ASC TERT1
Immunofluorescent staining of human cell line ASC TERT1 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/1749_G1_8_cr580497afc9e61_selected.jpg
Normal Tissue
Figure 2 High expression in adipose tissue
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_3_7_val_selected.jpg
Normal Tissue
Figure 3 Low expression in cerebral cortex
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5_val_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+, HBF TERT88, HSkMC)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144891-AGTR1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- AGTR1
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Angiotensin II receptor type 1
- Biological Process
- Host-virus interaction
- Molecular Function
- G-protein coupled receptor, Receptor, Transducer
- Cellular Localization
- Vesicles
- Introduction
- Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
- Alternative Names
- AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R
- Gene ID
- 185
- UniProt ID
- P30556
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0425-YC289. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "AGTR1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1660z | Mouse Anti-AGTR1 Recombinant Antibody (MOB-1660z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| HPAB-J0030-YC | Mouse Anti-AGTR1 Recombinant Antibody (HPAB-J0030-YC) | ELISA, FuncS | Mouse IgG |
| HPAB-J0031-YC | Mouse Anti-AGTR1 Recombinant Antibody (HPAB-J0031-YC) | ELISA | Mouse IgG |
| HPAB-J0032-YC | Human Anti-AGTR1 Recombinant Antibody (HPAB-J0032-YC) | ELISA | Humanized IgG |
| HPAB-J0033-YC | Human Anti-AGTR1 Recombinant Antibody (HPAB-J0033-YC) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0104 | Hi-Affi™ Rabbit Anti-AGTR1 Recombinant Antibody (clone DS104AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0030-YC-S(P) | Mouse Anti-AGTR1 Recombinant Antibody; scFv Fragment (HPAB-J0030-YC-S(P)) | ELISA, FuncS | Mouse scFv |
| HPAB-J0031-YC-S(P) | Mouse Anti-AGTR1 Recombinant Antibody; scFv Fragment (HPAB-J0031-YC-S(P)) | ELISA | Mouse scFv |
| HPAB-J0032-YC-S(P) | Human Anti-AGTR1 Recombinant Antibody; scFv Fragment (HPAB-J0032-YC-S(P)) | ELISA | Humanized scFv |
| HPAB-J0033-YC-S(P) | Human Anti-AGTR1 Recombinant Antibody; scFv Fragment (HPAB-J0033-YC-S(P)) | ELISA | Humanized scFv |
| HPAB-J0034-YC-S(P) | Human Anti-AGTR1 Recombinant Antibody; scFv Fragment (HPAB-J0034-YC-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0030-YC-F(E) | Mouse Anti-AGTR1 Recombinant Antibody; Fab Fragment (HPAB-J0030-YC-F(E)) | ELISA, FuncS | Mouse Fab |
| HPAB-J0031-YC-F(E) | Mouse Anti-AGTR1 Recombinant Antibody; Fab Fragment (HPAB-J0031-YC-F(E)) | ELISA | Mouse Fab |
| HPAB-J0032-YC-F(E) | Human Anti-AGTR1 Recombinant Antibody; Fab Fragment (HPAB-J0032-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-J0033-YC-F(E) | Human Anti-AGTR1 Recombinant Antibody; Fab Fragment (HPAB-J0033-YC-F(E)) | ELISA | Humanized Fab |
| HPAB-J0034-YC-F(E) | Human Anti-AGTR1 Recombinant Antibody; Fab Fragment (HPAB-J0034-YC-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NBD-0007-YJ-VHH | Camelid Anti-AGTR1 Recombinant Single Domain Antibody (NBD-0007-YJ-VHH) | ELISA, FC, FuncS | Camelid VHH |
| NBD-0008-YJ-VHH | Camelid Anti-AGTR1 Recombinant Single Domain Antibody (NBD-0008-YJ-VHH) | ELISA, FC, FuncS | Camelid VHH |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: WB, ELISA, FC, IP, FuncS, IF, Neut
-2.jpg)
Application: IB, ELISA, FC, FuncS
-3-1.png)
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FuncS
Application: ELISA, FC
Application: ELISA, Neut
Application: ELISA, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
