Camelid Anti-AGTR1 Recombinant Single Domain Antibody (NBD-0007-YJ-VHH) (CAT#: NBD-0007-YJ-VHH)
This product is a recombinant Llama single domain antibody that recognizes Human AGTR1. AT110 exhibited the highest degree of specificity for agonist-bound AT1R, and it retains this exquisite specificity as a purified protein, co-immunoprecipitating with the AT1R only in the presence of agonists such as AngII.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/1749_G1_8_cr580497afc9e61_selected.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/1749_G1_8_cr580497afc9e61_selected.jpg
Figure 2 High expression in adipose tissue
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_3_7_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_3_7_val_selected.jpg
Figure 3 Low expression in cerebral cortex
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5_val_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/3596/11017_B_7_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+, HBF TERT88, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144891-AGTR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000144891-AGTR1
Specifications
- Host Species
- Camelid
- Type
- Camelid VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- NBD-0007-YJ-VHH
- Applications
- ELISA, FC, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This sdAb has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry, Functional Assay.
Target
- Alternative Names
- AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B; type-1 angiotensin II receptor; type-1B angiotensin II receptor
- Gene ID
- 185
- UniProt ID
- P30556
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1660z | Mouse Anti-AGTR1 Recombinant Antibody (MOB-1660z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| HPAB-J0030-YC | Mouse Anti-AGTR1 Recombinant Antibody (HPAB-J0030-YC) | ELISA, FuncS | Mouse IgG |
| HPAB-J0031-YC | Mouse Anti-AGTR1 Recombinant Antibody (HPAB-J0031-YC) | ELISA | Mouse IgG |
| HPAB-J0032-YC | Human Anti-AGTR1 Recombinant Antibody (HPAB-J0032-YC) | ELISA | Humanized IgG |
| ZG-0535J | Rabbit Anti-AGTR1 Recombinant Antibody (clone 4A9) | ELISA, WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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