Recombinant Anti-AMHR2 Vesicular Antibody, EV Displayed (VS-0425-YC299) (CAT#: VS-0425-YC299)

• Application
• ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• AMHR2

• Host Animal
• Mouse

• Antibody Isotype
• IgG1 kappa

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein G

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Anti-Mullerian hormone receptor type 2

• Molecular Function
• Kinase, Receptor, Serine/threonine-protein kinase, Transferase

• Cellular Localization
• Vesicles, Nucleoplasm, Cytosol

• Introduction
• This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]

• Alternative Names
• MISR2, MISRII

• Gene ID
• 269

• UniProt ID
• Q16671

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