Recombinant Anti-AMHR2 Vesicular Antibody, EV Displayed (VS-0425-YC299)
CAT#: VS-0425-YC299
The Recombinant Anti-AMHR2 Vesicular Antibody, EV Displayed (VS-0425-YC299) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to AMHR2-expressed cells or tissues. The AMHR2 is a receptor for anti-Mullerian hormone, affecting male differentiation by preventing the development of Mullerian ducts. Mutations cause persistent Mullerian duct syndrome.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nucleoplasm, cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/60228/1825_H2_27_cr5abb93a3dd6f8_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69636/1512_E10_5_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/60228/1519_G11_1_blue_red_green.jpg
Subcellular Location
Figure 4 IF staining of human cell line A-434
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/60228/1504_D8_1_blue_red_green.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (HEL, K-562)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135409-AMHR2
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- AMHR2
- Host Animal
- Mouse
- Antibody Isotype
- IgG1 kappa
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein G
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Anti-Mullerian hormone receptor type 2
- Molecular Function
- Kinase, Receptor, Serine/threonine-protein kinase, Transferase
- Cellular Localization
- Vesicles, Nucleoplasm, Cytosol
- Introduction
- This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
- Alternative Names
- MISR2, MISRII
- Gene ID
- 269
- UniProt ID
- Q16671
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-56 | Recombinant Anti-AMHR2 Antibody | WB, ELISA, IHC, FuncS | IgG |
| MOB-57 | Recombinant Anti-AMHR-II Antibody | WB, IP, FuncS | IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-56-F(E) | Recombinant Anti-AMHR2 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| MOB-57-F(E) | Recombinant Anti-AMHR-II Antibody Fab Fragment | FC, IP, FuncS | Fab |
| MHH-56-F(E) | Recombinant Human Anti-AMHR2 Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| MHH-57-F(E) | Recombinant Human Anti-AMHR-II Antibody Fab Fragment | WB, IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-56-S(P) | Recombinant Anti-AMHR2 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| MOB-57-S(P) | Recombinant Anti-AMHR-II Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
| MHH-56-S(P) | Recombinant Human Anti-AMHR2 Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| MHH-57-S(P) | Recombinant Human Anti-AMHR-II Antibody scFv Fragment | FC, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0757CLV | Mouse Anti-AMHR2 Recombinant Antibody (TAB-0757CLV) | FC | Mouse IgG1, κ |
| TAB-0757CLV-F(E) | Mouse Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0757CLV-F(E)) | FC | Mouse Fab |
| TAB-0757CLV-S(P) | Mouse Anti-AMHR2 Recombinant Antibody; scFv Fragment (TAB-0757CLV-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0758CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0758CLV) | ELISA, SPR, FuncS | Humanized IgG |
| TAB-0759CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0759CLV) | ELISA, SPR, FuncS | Humanized IgG |
| TAB-0760CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0760CLV) | ELISA, SPR, FuncS | Humanized IgG |
| TAB-0761CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0761CLV) | ELISA, SPR, FuncS | Humanized IgG |
| TAB-0762CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0762CLV) | ELISA, SPR, FuncS | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0163 | Hi-Affi™ Rabbit Anti-AMHR2 Recombinant Antibody (clone DS163AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY14 | Human Anti-AMHR2 (clone 7) scFv-Fc Chimera | FC, SPR | Human IgG1, scFv-Fc |
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