Human Anti-AMHR2 (clone 7) scFv-Fc Chimera
CAT#: VS-0325-FY14
The anti-AMHR2 scFv-Fc antibody is a recombinant protein designed to specifically bind to the AMHR2 receptor, which plays a significant role in various physiological processes, including reproductive biology and certain pathologies. The scFv-Fc from clone 7 exhibits specific affinity for IGROV-1 cells that express the MISIIR.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nucleoplasm, cytosol & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/60228/1825_H2_27_cr5abb93a3dd6f8_selected.jpg
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human AMHR2
- Species Reactivity
- Human
- Clone
- clone 7
- Applications
- Flow Cytometry, Surface Plasmon Resonance
- Related Disease
- Human cervical cancer, prostate cancer, mammary epithelium, breast cancer, breast fibroadnoma, breast tumor, ductal carcinoma
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Anti-Mullerian Hormone Receptor Type 2; Muellerian Inhibiting Substance Type II Receptor; Anti-Muellerian Hormone Type II Receptor; AMH Type II Receptor; MIS Type II Receptor; EC 2.7.11.30; MISRII; MISR2
- Gene ID
- 269
- UniProt ID
- Q16671
- Long Name
- Anti-Mullerian Hormone Receptor Type 2
- Sequence Similarities
- Belongs to the protein kinase superfamily.
- Cellular Localization
- Membrane
- Post Translation Modifications
- Glycosylation at Asn66 and Asn119
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 2 sites
- Protein Refseq
- XP_011536475.1; XP_011536476.1; XP_011536478.1; XP_011536480.1; XP_011536481.1
- Function
- On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases.
Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
Receptor for anti-Muellerian hormone.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-56-F(E) | Recombinant Anti-AMHR2 Antibody Fab Fragment | FC, WB, FuncS | Fab |
| MOB-57-F(E) | Recombinant Anti-AMHR-II Antibody Fab Fragment | FC, IP, FuncS | Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-56-S(P) | Recombinant Anti-AMHR2 Antibody scFv Fragment | FC, IP, FuncS | scFv |
| MOB-57-S(P) | Recombinant Anti-AMHR-II Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
| MHH-56-S(P) | Recombinant Human Anti-AMHR2 Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| MHH-57-S(P) | Recombinant Human Anti-AMHR-II Antibody scFv Fragment | FC, WB, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0757CLV | Mouse Anti-AMHR2 Recombinant Antibody (TAB-0757CLV) | FC | Mouse IgG1, κ |
| TAB-0757CLV-F(E) | Mouse Anti-AMHR2 Recombinant Antibody; Fab Fragment (TAB-0757CLV-F(E)) | FC | Mouse Fab |
| TAB-0757CLV-S(P) | Mouse Anti-AMHR2 Recombinant Antibody; scFv Fragment (TAB-0757CLV-S(P)) | FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0758CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0758CLV) | ELISA, SPR, FuncS | Humanized IgG |
| TAB-0759CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0759CLV) | ELISA, SPR, FuncS | Humanized IgG |
| TAB-0760CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0760CLV) | ELISA, SPR, FuncS | Humanized IgG |
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| TAB-0762CLV | Human Anti-AMHR2 Recombinant Antibody (TAB-0762CLV) | ELISA, SPR, FuncS | Humanized IgG |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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