Recombinant Anti-ASIC1 Vesicular Antibody, EV Displayed (VS-0425-YC480)
CAT#: VS-0425-YC480
The Recombinant Anti-ASIC1 Vesicular Antibody, EV Displayed (VS-0425-YC480) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ASIC1-expressed cells or tissues. The ASIC1 is an ion channel involved in neurotransmission and processes like pain and touch sensation.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1671_H11_1_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line HEK293
Immunofluorescent staining of human cell line HEK293 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1043_G12_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line PC-3
Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1218_D3_2_blue_red_green.jpg
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ASIC1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Acid sensing ion channel subunit 1
- Biological Process
- Calcium transport, Ion transport, Sodium transport, Transport
- Molecular Function
- Ion channel, Sodium channel
- Cellular Localization
- Golgi apparatus, Plasma membrane
- Introduction
- This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]
- Alternative Names
- ACCN2, BNaC2, hBNaC2
- Gene ID
- 41
- UniProt ID
- P78348
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "ASIC1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-226-VHH | Recombinant Anti-Human ASIC1 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1046CLV | Human Anti-ASIC1 Recombinant Antibody (TAB-1046CLV) | ELISA | Human IgG4 |
| TAB-1047CLV | Human Anti-ASIC1 Recombinant Antibody (TAB-1047CLV) | ELISA | Human IgG4 |
| TAB-1048CLV | Human Anti-ASIC1 Recombinant Antibody (TAB-1048CLV) | ELISA | Human IgG4 |
| TAB-1049CLV | Human Anti-ASIC1 Recombinant Antibody (TAB-1049CLV) | ELISA | Human IgG4 |
| TAB-1050CLV | Human Anti-ASIC1 Recombinant Antibody (TAB-1050CLV) | ELISA | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1028CLV-S(P) | Mouse Anti-ASIC1 Recombinant Antibody (TAB-1028CLV-S(P)); scFv Fragment | ELISA | Mouse scFv |
| TAB-1029CLV-S(P) | Mouse Anti-ASIC1 Recombinant Antibody (TAB-1029CLV-S(P)); scFv Fragment | ELISA | Mouse scFv |
| TAB-1030CLV-S(P) | Mouse Anti-ASIC1 Recombinant Antibody (TAB-1030CLV-S(P)); scFv Fragment | ELISA | Mouse scFv |
| TAB-1031CLV-S(P) | Mouse Anti-ASIC1 Recombinant Antibody (TAB-1031CLV-S(P)); scFv Fragment | ELISA | Mouse scFv |
| TAB-1032CLV-S(P) | Mouse Anti-ASIC1 Recombinant Antibody (TAB-1032CLV-S(P)); scFv Fragment | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1625-CN | Rabbit Anti-ASIC1 Polyclonal Antibody (MRO-1625-CN) | WB, IHC, FC | Rabbit IgG |
| HPAB-M0262-YC | Human Anti-ASIC1 Recombinant Antibody (clone M/YC-3) | ELISA, IF | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0262-YC-S(P) | Human Anti-ASIC1 Recombinant Antibody (clone M/YC-3); scFv Fragment | ELISA, IF | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0262-YC-F(E) | Human Anti-ASIC1 Recombinant Antibody (clone M/YC-3); Fab Fragment | ELISA, IF | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY556 | Anti-ASIC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY557 | Anti-Mouse ASIC1 Immunohistochemistry Kit | IHC |
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