Human Anti-ASIC1 Recombinant Antibody (clone M/YC-3); Fab Fragment (CAT#: HPAB-M0262-YC-F(E))
The antibody is obtained by screening a holistic single-chain antibody phage library containing no mouse source or other foreign protein components, the obtained single-chain antibody can be easily transformed into the holistic antibody IgG, and the applied antibody is an ASICl channel protein. The antibody can specifically recognize the human ASICl channels of surfaces of cells and has an effect on restraining the activity of the channels.
Specific Inquiry
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1671_H11_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1671_H11_1_selected.jpg
Figure 2 IF staining of human cell line HEK293
(Immunofluorescent staining of human cell line HEK293 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1043_G12_2_blue_red_green.jpg
(Immunofluorescent staining of human cell line HEK293 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1043_G12_2_blue_red_green.jpg
Figure 3 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1218_D3_2_blue_red_green.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/58870/1218_D3_2_blue_red_green.jpg
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human ASIC1
- Species Reactivity
- Human
- Clone
- M/YC-3
- Applications
- ELISA, IF
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Acid Sensing Ion Channel Subunit 1; Amiloride-Sensitive Cation Channel 2, Neuronal; Acid Sensing (Proton Gated) Ion Channel 1; Brain Sodium Channel 2; ACCN2; BNaC2;
- Gene ID
- 41
- UniProt ID
- P78348
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Single Domain Antibody Products
Chimeric Antibody Products
Human Antibody Products
IgG Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-226-VHH | Recombinant Anti-Human ASIC1 VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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