Recombinant Anti-CD320 Vesicular Antibody, EV Displayed (VS-0425-YC653) (CAT#: VS-0425-YC653)
The Recombinant Anti-CD320 Vesicular Antibody, EV Displayed (VS-0425-YC653) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD320-expressed cells or tissues. CD320 is a protein associated with diseases like transient methylmalonic aciduria due to transcobalamin receptor defect. This is involved in metabolic pathways and features growth factor and cobalamin binding activities.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73489/1433_C7_1_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73489/1433_C7_1_selected.jpg

Figure 2 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in a subset of reaction center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/ihc_selected.jpg
(Immunohistochemical staining of human lymph node shows moderate cytoplasmic positivity in a subset of reaction center cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/ihc_selected.jpg

Figure 3 Cerebral cortex
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_B_8_5.jpg
(Glial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_B_8_5.jpg

Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_A_9_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_A_9_4.jpg

Figure 5 Testis
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_A_5_6.jpg
(Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_A_5_6.jpg

Figure 6 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_A_9_8.jpg
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/14500/34214_A_9_8.jpg

Figure 7 RNA cell line category: Cell line enhanced (NB-4, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167775-CD320
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167775-CD320
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD320
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD320 molecule
- Molecular Function
- Growth factor
- Cellular Localization
- Vesicles
- Introduction
- CD320 (CD320 Molecule) is a Protein Coding gene. Diseases associated with CD320 include Methylmalonic Aciduria, Transient, Due To Transcobalamin Receptor Defect and Methylmalonic Acidemia Due To Transcobalamin Receptor Defect. Among its related pathways are Diseases of metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include growth factor activity and cobalamin binding.
- Alternative Names
- 8D6, 8D6A, TCblR
- Gene ID
- 51293
- UniProt ID
- Q9NPF0
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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CAT | Product Name | Application | Type |
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TAB-120CL | Anti-Human CD320 Recombinant Antibody | FuncS | Antibody |
HPAB-0054CQ | Mouse Anti-CD320 Recombinant Antibody (HPAB-0054CQ) | ELISA, FC, IF | Mouse IgG, κ |
HPAB-0055CQ | Mouse Anti-CD320 Recombinant Antibody (HPAB-0055CQ) | ELISA, FC | Mouse IgG, κ |
HPAB-0056CQ | Mouse Anti-CD320 Recombinant Antibody (HPAB-0056CQ) | ELISA, FC, Block | Mouse IgG, κ |
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