Recombinant Anti-CD3D Vesicular Antibody, EV Displayed (VS-0425-YC234)
CAT#: VS-0425-YC234
The Recombinant Anti-CD3D Vesicular Antibody, EV Displayed (VS-0425-YC234) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD3D-expressed cells or tissues. The CD3D is a protein involved in signaling pathways, linked to immunodeficiency conditions like T-B+ Severe Combined Immunodeficiency.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line BJ
Immunofluorescent staining of human cell line JURKAT shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71778/1970_F1_3_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (JURKAT, MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167286-CD3D
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Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD3D
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD3 delta subunit of T-cell receptor complex
- Biological Process
- Adaptive immunity, Immunity
- Molecular Function
- Receptor
- Cellular Localization
- Endoplasmic reticulum, Vesicles
- Introduction
- CD3D (CD3d Molecule) is a Protein Coding gene. Diseases associated with CD3D include Immunodeficiency 19 and T-B+ Severe Combined Immunodeficiency Due To Cd3delta/Cd3epsilon/Cd3zeta. Among its related pathways are G-protein signaling N-RAS regulation pathway and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and transmembrane signaling receptor activity. An important paralog of this gene is CD3G.
- Alternative Names
- CD3-DELTA, CD3DELTA, T3D
- Gene ID
- 915
- UniProt ID
- P04234
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Related Diseases
Primary Immunodeficiency
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0703-FY-S(P) | Mouse Anti-CD3D Recombinant Antibody (clone AB002); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0722-FY-S(P) | Mouse Anti-CD3D Recombinant Antibody (clone AB039); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0381-FY-S(P) | Human Anti-CD3D Recombinant Antibody; scFv Fragment (HPAB-0381-FY-S(P)) | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0382-FY-S(P) | Human Anti-CD3D Recombinant Antibody; scFv Fragment (HPAB-0382-FY-S(P)) | Activ | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0381-FY-F(E) | Human Anti-CD3D Recombinant Antibody; Fab Fragment (HPAB-0381-FY-F(E)) | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0382-FY-F(E) | Human Anti-CD3D Recombinant Antibody; Fab Fragment (HPAB-0382-FY-F(E)) | Activ | Human Fab |
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