Recombinant Anti-CD53 Vesicular Antibody, EV Displayed (VS-0425-YC686)
CAT#: VS-0425-YC686
The Recombinant Anti-CD53 Vesicular Antibody, EV Displayed (VS-0425-YC686) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD53-expressed cells or tissues. CD53 enables identically protein binding and is involved in receptor clustering and myoblast fusion regulation, located in the cell surface, with a human ortholog.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_B_7_5.jpg
Normal Tissue
Figure 2 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_7_4.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_8_5.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_9_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, HMC-1, Karpas-707, U-266/70, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143119-CD53
❮
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Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD53
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD53 molecule
- Introduction
- Predicted to enable identical protein binding activity and protein-membrane adaptor activity. Predicted to be involved in positive regulation of myoblast fusion and receptor clustering. Located in cell surface. Orthologous to human CD53 (CD53 molecule).
- Alternative Names
- OX44, Ox-44
- Gene ID
- 24251
- UniProt ID
- P24485
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| MOB-1208z | Mouse Anti-CD53 Recombinant Antibody (clone 44C8) | WB, FC, IHC, IP, FuncS | Mouse IgG1 |
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| MOB-0509CT | Mouse Anti-CD53 Recombinant Antibody (clone IJ30), APC | FC | Mouse IgG1 |
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| MOR-0569 | Hi-Affi™ Rabbit Anti-CD53 Recombinant Antibody (clone DS569AB) | WB, IHC, ICC | Rabbit IgG |
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| FAMAB-1646CQ | Mouse Anti-CD53 Recombinant Antibody (clone OX44) | IHC-P, IP, FC, IHC-Fr | Mouse IgG1 |
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| VS3-CJ746 | Mouse Anti-CD53 Recombinant Antibody (clone C53-2) | IF, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
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| VS3-XY366 | Mouse Anti-CD53 Recombinant Antibody, FITC (clone 4AC53-2) | FC, IF | Mouse IgG2a |
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| VS-0724-YC542 | AbPlus™ Anti-CD53 Magnetic Beads (VS-0724-YC542) | IP, Protein Purification |
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| VS-0724-YC544 | AbPlus™ Anti-Cd53 Magnetic Beads (VS-0724-YC544) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1199 | Anti-CD53 Immunohistochemistry Kit | IHC |
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