Recombinant Anti-CD53 Vesicular Antibody, EV Displayed (VS-0425-YC686) (CAT#: VS-0425-YC686)
The Recombinant Anti-CD53 Vesicular Antibody, EV Displayed (VS-0425-YC686) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD53-expressed cells or tissues. CD53 enables identically protein binding and is involved in receptor clustering and myoblast fusion regulation, located in the cell surface, with a human ortholog.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_B_7_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_B_7_5.jpg
Figure 2 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_7_4.jpg
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_7_4.jpg
Figure 3 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_8_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_8_5.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_9_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/47216/108620_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, HMC-1, Karpas-707, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143119-CD53
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143119-CD53
Figure 5 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, HMC-1, Karpas-707, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143119-CD53
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000143119-CD53
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD53
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Rat
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD53 molecule
- Introduction
- Predicted to enable identical protein binding activity and protein-membrane adaptor activity. Predicted to be involved in positive regulation of myoblast fusion and receptor clustering. Located in cell surface. Orthologous to human CD53 (CD53 molecule).
- Alternative Names
- OX44, Ox-44
- Gene ID
- 24251
- UniProt ID
- P24485
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1208z | Mouse Anti-CD53 Recombinant Antibody (clone 44C8) | WB, FC, IHC, IP, FuncS | Mouse IgG1 |
| MOB-0509CT | Mouse Anti-CD53 Recombinant Antibody (clone IJ30), APC | FC | Mouse IgG1 |
| VS3-CJ746 | Mouse Anti-CD53 Recombinant Antibody (clone C53-2) | IF, FC | Mouse IgG2a |
| VS3-XY366 | Mouse Anti-CD53 Recombinant Antibody, FITC (clone 4AC53-2) | FC, IF | Mouse IgG2a |
| VS3-XY3300 | Rabbit Anti-CD53 Recombinant Antibody (clone R01-8U5) | WB, IHC-P, ICC, IF, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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