Recombinant Anti-CD68 Vesicular Antibody, EV Displayed (VS-0425-YC687)
CAT#: VS-0425-YC687
The Recombinant Anti-CD68 Vesicular Antibody, EV Displayed (VS-0425-YC687) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CD68-expressed cells or tissues. CD68 plays roles in lipopolysaccharide response and oxidized LDL particle stimuli, located in lysosomes and plasma membranes, with expression in various organs.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51/207_B3_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51/208_B3_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48982/158158_B_8_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48982/158158_A_7_8.jpg
Normal Tissue
Figure 6 Spleen
Cells in red pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48982/158158_B_8_4.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000129226-CD68
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CD68
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Mouse
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- CD68 molecule
- Cellular Localization
- Golgi apparatus, Vesicles
- Introduction
- Involved in several processes, including cellular response to lipopolysaccharide; cellular response to oxidised low-density lipoprotein particle stimulus; and negative regulation of dendritic cell antigen processing and presentation. Located in lysosome and plasma membrane. Is expressed in several structures, including central nervous system; heart blood vessel; liver; spleen; and tooth. Orthologous to human CD68 (CD68 molecule).
- Alternative Names
- Lamp4, Scard1, gp110
- Gene ID
- 12514
- UniProt ID
- A0A0R4J1C8
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MSDS
COA
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| MOB-1181z | Mouse Anti-CD68 Recombinant Antibody (clone 24H1) | ELISA, FC, ICC, IF, IHC, WB | Mouse IgG1 |
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| CAT | Product Name | Application | Type |
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| MRO-0314-CN | Rabbit Anti-CD68 Recombinant Antibody (clone CBACN-120) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| FAMAB-1076CQ | Human Anti-CD68 Recombinant Antibody (clone Y1/82A) | FACS, WB, IF, IHC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1077CQ | Human Anti-CD68 Recombinant Antibody (clone Y-2/131/47) | ICC, IP, WB | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY108 | Mouse Anti-NHP CD68 Recombinant Antibody (clone KP1) | IHC, IF | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
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| VS-0225-XY65 | CytoStream™ Mouse Anti-CD68 Recombinant Antibody (clone Y1/82A) | FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY371 | Anti-CD68 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC171 | CytoStream™ Mouse Anti-CD68 Recombinant Antibody (VS13-YC171) | WB, IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1210 | Anti-Rat CD68 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1211 | Anti-Mouse CD68 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1212 | Anti-Monkey CD68 Immunohistochemistry Kit | IHC |
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