CytoStream™ Mouse Anti-CD68 Recombinant Antibody (VS13-YC171)
CAT#: VS13-YC171
The CytoStream™ Mouse Anti-CD68 Recombinant Antibody is specific for human CD68. CD68, a marker in immune lineage pathways, impacts diseases like granular cell tumors through scavenger pathway mechanisms that influence cellular modulation. The anti-CD68 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51/207_B3_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51/208_B3_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48982/158158_B_8_5.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48982/158158_A_7_8.jpg
Normal Tissue
Figure 6 Spleen
Cells in red pulp
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48982/158158_B_8_4.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, U-87 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000129226-CD68
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Specifications
- Immunogen
- Recombinant human CD68, aa 320-354.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human CD68
- Species Reactivity
- Human
- Applications
- WB, IHC-P, FC
- Conjugate
- NONE
- Related Disease
- Granular Cell Tumor and Breast Granular Cell Tumor
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 50% Glycerol and 0.2% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/1000-1/2000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- CD68 Molecule; CD68 Antigen; Scavenger Receptor Class D, Member 1; Macrophage Antigen CD68; GP110; Macrosialin; SCARD1; LAMP4;
- Gene ID
- 968
- UniProt ID
- P34810
- Long Name
- CD68 Molecule
- Sequence Similarities
- Belongs to the LAMP family.
- Cellular Localization
- Cell membrane; Endosome membrane; Lysosome membrane
- Protein Refseq
- NP_001035148.1; NP_001242.2
- Function
- Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "CD68"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0576 | Hi-Affi™ Rabbit Anti-CD68 Recombinant Antibody (clone DS576AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0314-CN | Rabbit Anti-CD68 Recombinant Antibody (clone CBACN-120) | WB | Rabbit IgG |
| FAMAB-1076CQ | Human Anti-CD68 Recombinant Antibody (clone Y1/82A) | FACS, WB, IF, IHC | Human IgG1 |
| FAMAB-1077CQ | Human Anti-CD68 Recombinant Antibody (clone Y-2/131/47) | ICC, IP, WB | Human IgG1 |
| VS3-WK80 | Mouse Anti-CD68 Recombinant Antibody (clone F3-D7) | WB, IHC, ICC, FC | Mouse IgG1 |
| VS3-WK92 | Mouse Anti-CD68 Recombinant Antibody (clone F7-C6) | WB, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY108 | Mouse Anti-NHP CD68 Recombinant Antibody (clone KP1) | IHC, IF | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY65 | CytoStream™ Mouse Anti-CD68 Recombinant Antibody (clone Y1/82A) | FC | Mouse IgG2b, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY371 | Anti-CD68 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1210 | Anti-Rat CD68 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1211 | Anti-Mouse CD68 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1212 | Anti-Monkey CD68 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC687 | Recombinant Anti-CD68 Vesicular Antibody, EV Displayed (VS-0425-YC687) | ELISA, FC, Cell-uptake |
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