Recombinant Anti-CDH15 Vesicular Antibody, EV Displayed (VS-0425-YC603) (CAT#: VS-0425-YC603)
The Recombinant Anti-CDH15 Vesicular Antibody, EV Displayed (VS-0425-YC603) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH15-expressed cells or tissues. CDH15 is a cadherin associated with intellectual disabilities and hypotrichosis. It participates in pathways like ERK signaling and has a related gene paralog, CDH4.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line RH-30
(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/1165_D3_1_selected.jpg
(Immunofluorescent staining of human cell line RH-30 shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/1165_D3_1_selected.jpg

Figure 2 High expression in skeletal muscle
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/26256_B_3_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/26256_B_3_6_val_selected.jpg

Figure 3 Low expression in skin 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/26256_B_8_1_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/26256_B_8_1_val_selected.jpg

Figure 4 Skeletal muscle
(Myocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/26256_B_3_6.jpg
(Myocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9139/26256_B_3_6.jpg

Figure 5 RNA cell line category: Cell line enriched (RH-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000129910-CDH15
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000129910-CDH15
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDH15
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cadherin 15
- Biological Process
- Cell adhesion
- Cellular Localization
- Golgi apparatus, Plasma membrane
- Introduction
- CDH15 (Cadherin 15) is a Protein Coding gene. Diseases associated with CDH15 include Autosomal Dominant Non-Syndromic Intellectual Disability and Hypotrichosis, Congenital, With Juvenile Macular Dystrophy. Among its related pathways are ERK Signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH4.
- Alternative Names
- CDH14, CDH3
- Gene ID
- 1013
- UniProt ID
- P55291
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0615 | Hi-Affi™ Rabbit Anti-CDH15 Recombinant Antibody (clone DS615AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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